Which of the following is true about ADH and oxytocin?
Anonymous Quiz
13%
They are synthesized and stored in posterior pituitary
79%
They are synthesized by hypothalamus and stored in post.pituitary
6%
Synthesized by Anterior pituitary
2%
Stored in the Anterior pituitary
When osmotic pressure of the plasma increases, ADH secretion will increase
Anonymous Quiz
75%
True
25%
False
All of the following increase ADH secretion except
Anonymous Quiz
17%
Pain
11%
Emotions
26%
Alcohol intake
30%
Angiotensin 2
15%
Nicotine
Patient presented with water retention& hyponatremia, what is the most possible cause?
Anonymous Quiz
40%
Deficiency of ADH secretion
40%
ADH- Secreting tumor
19%
None of the above
All of these are manifestation of Diabetes insipidus patient except
Anonymous Quiz
5%
Polydipsia
10%
Loss of vitamins in urine
31%
Increase BMR
55%
Decreased urine output
All of these effects are true about action of Oxytocin (on pregnant uterus) except
Anonymous Quiz
5%
Contraction, helps delivery
17%
After labor, helps involution of the uterus
49%
Stimulates post partum hemorrhage
29%
None of the above
👍1
Which of the following is true about OXYTOCIN action
Anonymous Quiz
32%
Milk retention
12%
Decrease ejaculation in males
39%
Help transport of sperms from vagina to uterine tubes
17%
Relaxtion of the uterus
👍1
Control of secretion of Oxytocin:
1- Suckling
2- labour: cervix dilatation
3- Coitus
4- Conditioned reflexes: milk ejection in women in response to sight and sound of the her baby
2- labour: cervix dilatation
3- Coitus
4- Conditioned reflexes: milk ejection in women in response to sight and sound of the her baby
‼️Which feedback mechanism is most commonly involved in regulating hormone secretion?
Anonymous Quiz
5%
Positive feedback
71%
Negative feedback
14%
Reflex control
10%
Feedforward control
✨How are hormones transported from the hypothalamus to the anterior pituitary?
Anonymous Quiz
21%
Axonal transmission through the hypothalamic-hypophysial tract
69%
Hypothalamic-hypophysial portal circulation
8%
Systemic blood circulation
3%
Passive diffusion across the median eminence
What is the basal level of Growth Hormone (GH) in normal adult humans?
Anonymous Quiz
21%
6 ng/ml
41%
1.5–3 ng/ml
21%
10 ng/ml
18%
0.5–1 ng/ml
How does GH secretion change with age?
Anonymous Quiz
14%
It increases continuously after adolescence
14%
It remains constant throughout life
51%
It decreases to about 25% of adolescent levels in old age
22%
It stops entirely after adolescence
‼️In which pattern is GH secreted?
Anonymous Quiz
22%
Continuous
30%
Pulsatile
41%
During sleep only
8%
Random
What is the basal level of (GH) in children or adolescents?
Anonymous Quiz
16%
1.5–3 ng/ml
48%
6 ng/ml
19%
10 ng/ml
16%
0.5–1 ng/ml
✨How does Growth Hormone (GH) affect bone growth before the closure of the epiphysis?
Anonymous Quiz
5%
It stops chondrogenesis, preventing any linear growth.
74%
It stimulates chondrogenesis, resulting in increased linear growth.
15%
It promotes osteoclast activity, leading to bone shortening.
5%
It inhibits osteoblast function, decreasing linear growth.
‼️‼️GH mostly affects bone growth by which
Anonymous Quiz
25%
Directly by acting on its receptor
48%
indirectly by acting on “ IGF-1 “
7%
None
20%
Both
✨After the closure of the epiphyses, how does (GH) affect bone growth?
Anonymous Quiz
0%
⬆️linear growth by⬆️ chondrogenesis.
75%
⬆️bone thickness by ⬆️ osteoblasts in the periosteum and membranous cavities.
17%
⬇️ any further bone growth once epiphyses are closed.
8%
⬇️ osteoblast activity and ❌ bone formation.
🔥Note ;
Bone thickness appears mostly in membranous bone ( skull , jaw)
Bone thickness appears mostly in membranous bone ( skull , jaw)
How does (GH) affect protein metabolism?
Anonymous Quiz
12%
It enhances amino acid transport into cells.
6%
It increases nuclear transcription of DNA to form RNA.
6%
It stimulates RNA translation to increase protein synthesis by ribosomes.
12%
It decreases catabolism of cell protein and amino acids.
64%
All of the above