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Actions of estrogen

I- On female sex organs:
1- The primary female sex organs (the ovaries):
a) It induces the growth and maturation of the graffian follicles.
b) It is essential for formation of the corpus luteum (by stimulating LH surge).
2- The secondary female sex organs:
a) Fallopian tubes: estrogen stimulates:
- Growth of its mucosal and muscular layers. - Its motility.
b) Uterus:
- It is responsible for the proliferative phase of the menstrual cycle.
- It stimulates growth of the myometrium, endometrial epithelium and glands.
- It increases uterine blood flow.
- It stimulates contractility of the myometrium.
- It increases sensitivity of the myometrium to the action of oxytocin.
c) Cervix: It makes the cervical mucus thin and alkaline which promotes the survival and
transport of sperms.
d) Vagina: It causes change of the vaginal epithelium into a stratified type which resists trauma.
II- On the female sex characters: estrogen is the feminizing hormone; it produces the following
changes in girls at puberty
a) Characteristic fat distribution: Fat is deposited in the breasts, lower abdomen, buttocks and
thighs (characteristic feminine contour).
b) Changes in the body configuration: Narrow shoulders & broad hips.
c) The skin is soft, smooth, more vascular and warm.
d) Feminine distribution of hair:
- Less body hair. - More scalp hair without frontal recession.
-The pubic hair is triangular with its base up.
e) The larynx and the vocal cords are not enlarged. So, the voice remains high pitched.
f) The breasts: It increases:
- The stromal tissues of breasts. - Development of the duct system.
- Fat deposition in the breast - blood flow of breast.
- Growth of the nipples and darkening of the areolas.
III- Psychological and behavioral changes:
Estrogens are also responsible for the psychological and behavioral changes that occur in girls at
puberty.
IV- General metabolic effects:
1- Anabolic effect on protein metabolism.
2-On bone:
a) It stimulates the osteoblastic activity.
b) It causes early union of the epiphysis๏ƒž so; the mature female is usually shorter than the
male.
3- It causes Na+ & water retention.
4- Cholesterol lowering effect
๐Ÿ‘2โค1
Actions of progesterone:


1- It is essential for occurrence & maintenance of pregnancy.
2- Uterus:
i- It promotes secretory changes of endometrium during the secretory phase of menstrual cycle.
ii- It prepares the uterus for implantation of the fertilized ovum.
iii- It decreases uterine contractions through decreasing myometrium sensitivity to oxytocin
(Which is essential for maintenance of pregnancy)
iv- It decreases the number of estrogen receptors in the endometrium.
3- Cervix: It makes the cervical mucus thick, tenacious and cellular
4- Vagina: It makes vaginal epithelium proliferate and become infiltrated by leucocytes
5- Breast: It promotes growth of the secretory acini of the breasts.
6 - Thermogenic effect: It increases the body temperature by about 0.5 โฐC in the second half of
menstrual cycle due to increased basal metabolic rate by about (5-10%)
7- On electrolyte and water balance:
๏‚ง Progesterone in large dose, it increases Na+ and water excretion.
๏‚ง But in small doses, it causes Na+ and water retention.
8- It prevents ovulation & menstruation during pregnancy: Through a negative feedback
mechanism by inhibition of LH secretion
โคโ€๐Ÿ”ฅ3โค2๐Ÿ˜ฑ1
ู…ูŽุง ุฎูŽุงุจูŽ ู…ูู†ู’ ูููŠ ุงูŽู„ู„ูŽู‘ู‡ู ูƒูŽุงู†ูŽ ุฑูŽุฌูŽุงู‡ูุŒ
ููŽุงููŽุฒู’ุนู’ ุฅูู„ูŽูŠู’ู‡ู ูˆูŽุฎูŽู„ูู‘ ุฐููƒู’ุฑู ุณููˆูŽุงู‡ู.โ™ก'

_ู‚ูŠุงู… ุงู„ู„ูŠู„ ูˆู…ุชุณูˆุด ุชุฏุนูˆู„ู†ุง๐Ÿค.
โค28๐Ÿฅฐ1
ุจุบุถ ุงู„ู†ุธุฑ ุนู† ุฃูŠ ุฏุฑุฌุงุช ุฃูˆ GPA
ุฅู† ุฃุฑู‚ุงู… ุชุชูƒุชุจ ุนู„ุดุงู† ุชุฏู„ ุนู„ูŠ ุงู„ู„ูŠ ุนู…ู„ุชู‡ ุทูˆู„ ุงู„ุชุฑู… ุดูŠุก ุธุงู„ู… ุฃูˆูŠ..
ุงู„ุฃูŠุงู… ุงู„ู„ูŠ ุจุชุตุญู‰ ููŠู‡ุง ู„ูˆุญุฏูƒ ุจุงู„ู„ูŠู„ ุฃูˆ ุงู„ูุฌุฑ ูˆุชุฐุงูƒุฑ ููŠ ุนุฒ ุงู„ุจุฑุฏ ูˆุงู„ุณู‡ุฑ ูˆุงู„ุชุนุจ ูˆุชูˆู‚ู ุญูŠุงุชูƒ ูˆู‡ูˆุงูŠุงุชูƒ ุจุณุจุจ ุฅู…ุชุญุงู†ุงุช ูˆุงู„ุญุฒู† ูˆุงู„ูˆุญุฏุฉ ูˆุงู„ู‚ู„ู‚ ูˆุนุฏู… ุงู†ุชุธุงู… ููŠ ุงู„ุงูƒู„ ูˆุจุนูŠุฏ ุนู† ุฃู‡ู„ูƒ ูƒู„ ุฏู‡ ุนู„ุดุงู† ุชุชุนู„ู… ูˆ ุชุทู„ุน ุดุฎุต ู†ุงุฌุญ ูƒู„ ุฏู‡ ูŠุชุฑุฌู… ู„ุฃุฑู‚ุงู… ุŸ!
ู…ู‡ู…ุง ุญุตู„ ูˆ ู…ู‡ู…ุง ุนู…ู„ุช ุฅูŠู‡ ุงูุชุฎุฑ ุจู†ูุณูƒ ูˆุจู…ุฌู‡ูˆุฏูƒ ุทุงู„ู…ุง ุนู…ู„ุช ุงู„ู„ูŠ ุนู„ูŠูƒโ™ฅ๏ธ
โค51๐Ÿฅฐ5๐Ÿ˜ข2๐Ÿคฉ2โšก1
ุตุจุงุญู ุงู„ุฎูŠุฑ.. ๐Ÿค

ยซุณูŽุชู†ุฏูŽู… ุญููŠู† ุชูŽุฑู‰ ุฃู†ุงุณู‹ุง ูƒุงู†ููˆุง ููŠ ู…ูุซู„ ุณู†ู‘ููƒ ูˆุธุฑููˆููƒุŒ ุดู…ุฑูˆุง ุนู† ุณูŽุงุนุฏ ุงู„ุฌุฏู‘ูุŒ ูˆูˆุถุนููˆุง ุนู„ู‰ ุฃูƒุชุงูู‡ูู… ุณูู„ุงุญ ุงู„ุนุฒู…ุŒ ูˆูููŠ ู‚ู„ููˆุจู‡ู… ุฒุงุฏู ุงู„ู‡ูู…ุฉุŒ ูˆุชุฑูƒููˆุง ุงู„ุชู‘ูŽูุงู‡ุงุช ุงู„ุดุจูƒููŠุฉ - ุงู„ู‘ูŽุชูŠ ุชูŽุดุบู„ ุจูู‡ุง ูŠูŽูˆู…ูƒ ูˆู„ูŠู„ุชูƒ ุงู„ุขู† - ูˆูŽุฑุงุก ุธูู‡ูˆุฑูู‡ู…...

‏ู‚ุฏู’ ูˆุตู„ููˆุง ุฅู„ู‰ ู…ูุจุชุบุงู‡ู…ุŒ ูˆู†ุงู„ููˆุง ู…ุฑุงุฏูŽู‡ู…ุŒ ูˆุชุฑู‰ ุฃู†ูƒ ู„ุง ุชูŽุฒุงู„ ููŠ ู…ูƒุงู†ูƒ ู„ู… ุชูŽุจุฑุญู‡!

‏ุงุณุชูŠู‚ุธ .. ูุงู„ุนูู…ุฑ ู‚ุตูŠุฑ!!!! ยป

#ู†ุตุงุฆุญ_ูˆุชูˆุฌูŠู‡ุงุช_ุฅู„ูŠ_ุทู„ุงุจ_ุงู„ุนู„ู…
โค22๐Ÿ˜ข2๐Ÿ‘1๐Ÿค”1
ุงู†ุง ุงุนุฑู ูˆุงุญุฏ ู‚ุงู„ูŠ ุงู„ู†ูŠูˆุฑูˆ ุฃุณู‡ู„ ู…ุงุฏุฉ ู‡ุชุงุฎุฏู‡ุง ูู‰ ุณู†ู‡ ุชุงู†ูŠุฉ ๐Ÿคก

ุชู‚ุฑูŠุจุง ูƒุงู† ู‚ุตุฏู‡ ูู‰ ุงู„ุณู…ุฑ ๐Ÿ’€โ˜ 
๐Ÿ˜ญ11๐Ÿคก5๐Ÿ˜ฑ2