Forwarded from Tommy Robinson News
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They jabbed half the world, leading to untold deaths and injuries, and could've just had garlic.
Studie zeigt, dass australischer Knoblauch Covid und Grippe mit einer Wirksamkeit von „99,9 Prozent“ abtötet
Berichten zufolge zeigt eine weltweit erste Studie, dass bestimmte australische Knoblauchsorten Covid und die Grippe mit „99,9-prozentiger Wirksamkeit“ töten – aber nicht alle sind mit den Ergebnissen einverstanden.
https://www.news.com.au/technology/science/human-body/study-finds-australian-garlic-kills-covid-and-flu-with-999-per-cent-efficacy/news-story/6e9dddf0aecf08e8d54f0c62242e6618
Berichten zufolge zeigt eine weltweit erste Studie, dass bestimmte australische Knoblauchsorten Covid und die Grippe mit „99,9-prozentiger Wirksamkeit“ töten – aber nicht alle sind mit den Ergebnissen einverstanden.
https://www.news.com.au/technology/science/human-body/study-finds-australian-garlic-kills-covid-and-flu-with-999-per-cent-efficacy/news-story/6e9dddf0aecf08e8d54f0c62242e6618
news
Garlic kills Covid with ‘99.9 per cent efficacy’
A world-first study which reportedly shows certain Australian garlic varieties kill Covid and the flu with “99.9 per cent efficacy” is yet to be officially published, while the industry body which commissioned the research has “not decided to release the…
Ein Artikel vom Bruder von Jane Burgermeister !
Es geht ihr gut !
https://lettersfromvienna.substack.com/p/jane-to-the-rescue
Es geht ihr gut !
https://lettersfromvienna.substack.com/p/jane-to-the-rescue
Substack
Jane to the Rescue
How my sister saved the world
Forwarded from Suavek
...
The face cream story
How the Corona scam became common belief
…..........................................................................................
An example from my own extended family.
It was the year 2022. My aunt Irene always knew everything "better". Despite being 85 at the time (now 86), she was quite physically fit. She is a former state swimming champion, was also active in sports dance ( in the 1960s ) and now swims her obligatory 1000 meters almost every day in the municipal swimming pool. After I had already warned Irene about the toxicity of the "vaccinations" at the beginning of 2021 and had also sent good information by email, she sought advice from a total of 7 doctors (!). According to them, 2 of them expressed concerns about the experimental substances and 5 were "in favor". Despite this, she has come to her ironclad conviction that she must protect her life with injections. She let it be known that she had a bad opinion of the two doctors. In 2022 she had already been "vaccinated" against Covid 4 times when she suddenly felt a slight cold. The PCR test was positive! She claimed to have lost her taste. On the same day she had the doctor prescribe Paxlovid for Covid (I also warned her about this drug in vain). When Irene came home with the medication, she quickly took the first pill. Then she washed her hands and face. It turned out that her face cream had an unusually strong effect on her taste. After washing her face, the food tasted good as usual. The scent of her face cream was the only thing that spoiled her sense of taste. Nevertheless, she finished taking the Paxlovid tablets one after the other, as prescribed : "better safe than sorry !".
At the beginning of 2023, Irene seemed to be allowed to experience a brief illumination of her "brain waves". She told me that she is not stupid because she can clearly observe that the number of diseases has increased. Now, in mid-2023, she can no longer remember this statement and because of my ( scientifically based ) opinion she declared me crazy a few days ago ( by phone ). I don't know whether it's a case of sudden dementia (she wasn't demented before!), or whether the inheritance smugglers in her area helped her to form an opinion in order to defame me, I don't know. Both are possible.
Irene was always very concerned about herself and her health. I see how the transition between normality and neurosis/hypochondria is blurred. The effects of the fear instilled in people through PsyOp have been devastating. One of the long-well-known effects of fear is (to put it in common parlance) the narrowing of the mind. It's a survival mode that dominates almost all thinking. Fear of death is a much simpler explanation than the other explanations why, for example, Irene ignored the arguments of the two critical doctors. Fear of death is the simplest explanation for why Irene, for example, ignored the arguments of the two critical doctors. For practical reasons, and being a medical layperson, I like the idea that preference should be given to the simplest theory of all that can exhaustively explain a person's behavior. What some call " the mass psychosis " is the sum of such individual fates. This "face cream story" is probably indicative of many individual fates in recent years.
https://www.youtube.com/watch?v=utDovM5a-cY
The face cream story
How the Corona scam became common belief
…..........................................................................................
An example from my own extended family.
It was the year 2022. My aunt Irene always knew everything "better". Despite being 85 at the time (now 86), she was quite physically fit. She is a former state swimming champion, was also active in sports dance ( in the 1960s ) and now swims her obligatory 1000 meters almost every day in the municipal swimming pool. After I had already warned Irene about the toxicity of the "vaccinations" at the beginning of 2021 and had also sent good information by email, she sought advice from a total of 7 doctors (!). According to them, 2 of them expressed concerns about the experimental substances and 5 were "in favor". Despite this, she has come to her ironclad conviction that she must protect her life with injections. She let it be known that she had a bad opinion of the two doctors. In 2022 she had already been "vaccinated" against Covid 4 times when she suddenly felt a slight cold. The PCR test was positive! She claimed to have lost her taste. On the same day she had the doctor prescribe Paxlovid for Covid (I also warned her about this drug in vain). When Irene came home with the medication, she quickly took the first pill. Then she washed her hands and face. It turned out that her face cream had an unusually strong effect on her taste. After washing her face, the food tasted good as usual. The scent of her face cream was the only thing that spoiled her sense of taste. Nevertheless, she finished taking the Paxlovid tablets one after the other, as prescribed : "better safe than sorry !".
At the beginning of 2023, Irene seemed to be allowed to experience a brief illumination of her "brain waves". She told me that she is not stupid because she can clearly observe that the number of diseases has increased. Now, in mid-2023, she can no longer remember this statement and because of my ( scientifically based ) opinion she declared me crazy a few days ago ( by phone ). I don't know whether it's a case of sudden dementia (she wasn't demented before!), or whether the inheritance smugglers in her area helped her to form an opinion in order to defame me, I don't know. Both are possible.
Irene was always very concerned about herself and her health. I see how the transition between normality and neurosis/hypochondria is blurred. The effects of the fear instilled in people through PsyOp have been devastating. One of the long-well-known effects of fear is (to put it in common parlance) the narrowing of the mind. It's a survival mode that dominates almost all thinking. Fear of death is a much simpler explanation than the other explanations why, for example, Irene ignored the arguments of the two critical doctors. Fear of death is the simplest explanation for why Irene, for example, ignored the arguments of the two critical doctors. For practical reasons, and being a medical layperson, I like the idea that preference should be given to the simplest theory of all that can exhaustively explain a person's behavior. What some call " the mass psychosis " is the sum of such individual fates. This "face cream story" is probably indicative of many individual fates in recent years.
https://www.youtube.com/watch?v=utDovM5a-cY
YouTube
Baldy Man Der Hypochonder
...
The face cream story
How the Corona scam became common belief
…..........................................................................................
A 100% authentic example from my own extended family.
It was the year 2022. My aunt Irene always knew everything "better". Despite being 85 at the time (now 86), she was quite physically fit. She is a former state swimming champion, was also active in sports dance ( in the 1960s ) and now swims her obligatory 1000 meters almost every day in the municipal swimming pool. After I had already warned Irene about the toxicity of the "vaccinations" at the beginning of 2021 and had also sent good information by email, she sought advice from a total of 7 doctors (!). According to them, 2 of them expressed concerns about the experimental substances and 5 were "in favor". Despite this, she has come to her ironclad conviction that she must protect her life with injections. She let it be known that she had a bad opinion of the two doctors. In 2022 she had already been "vaccinated" against Covid 4 times when she suddenly felt a slight cold. The PCR test was positive! She claimed to have lost her taste. On the same day she had the doctor prescribe Paxlovid for Covid (I also warned her about this drug in vain). When Irene came home with the medication, she quickly took the first pill. Then she washed her hands and face. It turned out that her face cream had an unusually strong effect on her taste. After washing her face, the food tasted good as usual. The scent of her face cream was the only thing that spoiled her sense of taste. Nevertheless, she finished taking the Paxlovid tablets one after the other, as prescribed : "better safe than sorry !".
At the beginning of 2023, Irene seemed to be allowed to experience a brief illumination of her "brain waves". She told me that she is not stupid because she can clearly observe that the number of diseases has increased. Now, in mid-2023, she can no longer remember this statement and because of my ( scientifically based ) opinion she declared me crazy a few days ago ( by phone ). I don't know whether it's a case of sudden dementia (she wasn't demented before!), or whether the inheritance smugglers in her area helped her to form an opinion in order to defame me, I don't know. Both are possible.
Irene was always very concerned about herself and her health. I see how the transition between normality and neurosis/hypochondria is blurred. The effects of the fear instilled in people through PsyOp have been devastating. One of the long-well-known effects of fear is (to put it in common parlance) the narrowing of the mind. It's a survival mode that dominates almost all thinking. Fear of death is a much simpler explanation than the other explanations why, for example, Irene ignored the arguments of the two critical doctors. Fear of death is the simplest explanation for why Irene, for example, ignored the arguments of the two critical doctors. For practical reasons, and being a medical layperson, I like the idea that preference should be given to the simplest theory of all that can exhaustively explain a person's behavior. What some call " the mass psychosis " is the sum of such individual fates. This "face cream story" is probably indicative of many individual fates in recent years.
https://www.youtube.com/watch?v=utDovM5a-cY
The face cream story
How the Corona scam became common belief
…..........................................................................................
A 100% authentic example from my own extended family.
It was the year 2022. My aunt Irene always knew everything "better". Despite being 85 at the time (now 86), she was quite physically fit. She is a former state swimming champion, was also active in sports dance ( in the 1960s ) and now swims her obligatory 1000 meters almost every day in the municipal swimming pool. After I had already warned Irene about the toxicity of the "vaccinations" at the beginning of 2021 and had also sent good information by email, she sought advice from a total of 7 doctors (!). According to them, 2 of them expressed concerns about the experimental substances and 5 were "in favor". Despite this, she has come to her ironclad conviction that she must protect her life with injections. She let it be known that she had a bad opinion of the two doctors. In 2022 she had already been "vaccinated" against Covid 4 times when she suddenly felt a slight cold. The PCR test was positive! She claimed to have lost her taste. On the same day she had the doctor prescribe Paxlovid for Covid (I also warned her about this drug in vain). When Irene came home with the medication, she quickly took the first pill. Then she washed her hands and face. It turned out that her face cream had an unusually strong effect on her taste. After washing her face, the food tasted good as usual. The scent of her face cream was the only thing that spoiled her sense of taste. Nevertheless, she finished taking the Paxlovid tablets one after the other, as prescribed : "better safe than sorry !".
At the beginning of 2023, Irene seemed to be allowed to experience a brief illumination of her "brain waves". She told me that she is not stupid because she can clearly observe that the number of diseases has increased. Now, in mid-2023, she can no longer remember this statement and because of my ( scientifically based ) opinion she declared me crazy a few days ago ( by phone ). I don't know whether it's a case of sudden dementia (she wasn't demented before!), or whether the inheritance smugglers in her area helped her to form an opinion in order to defame me, I don't know. Both are possible.
Irene was always very concerned about herself and her health. I see how the transition between normality and neurosis/hypochondria is blurred. The effects of the fear instilled in people through PsyOp have been devastating. One of the long-well-known effects of fear is (to put it in common parlance) the narrowing of the mind. It's a survival mode that dominates almost all thinking. Fear of death is a much simpler explanation than the other explanations why, for example, Irene ignored the arguments of the two critical doctors. Fear of death is the simplest explanation for why Irene, for example, ignored the arguments of the two critical doctors. For practical reasons, and being a medical layperson, I like the idea that preference should be given to the simplest theory of all that can exhaustively explain a person's behavior. What some call " the mass psychosis " is the sum of such individual fates. This "face cream story" is probably indicative of many individual fates in recent years.
https://www.youtube.com/watch?v=utDovM5a-cY
YouTube
Baldy Man Der Hypochonder
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...
Part 2 of : The face cream story
Part 2 of : The face cream story
Forwarded from Geradeausdenken: Freiheit statt WHO-Pandemievertrag, Diktatur verhindern, Kriegstreiber stoppen! Denkfilme, Talksendungen, Dokus
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AlterStinksack - Dr. Wolfgang Wodarg
https://www.bitchute.com/video/NopXZ4LAi4wD/ 1:40
@GERADEAUS_DENKEN
https://www.bitchute.com/video/NopXZ4LAi4wD/ 1:40
@GERADEAUS_DENKEN
Forwarded from Mit Bestechungen, Skandalen, Korruption zur NWO: Es kann nicht sein, was nicht sein darf! - Aufdecker, Enthüller, Whistleblower
AlterStinksack - Immer wieder dasselbe Spiel......
Wolfgang Wodarg zur "Impfung" gegen Schweinegrippe
07.04.2010
https://www.bitchute.com/video/nc838ZVcaPdh/ 6:34
Immer Neues @Aufdecker
Wolfgang Wodarg zur "Impfung" gegen Schweinegrippe
07.04.2010
https://www.bitchute.com/video/nc838ZVcaPdh/ 6:34
Immer Neues @Aufdecker
Forwarded from Deleted Account
The French have a reputation for constant protesting. They typically don't organize through political means.What does it actually change? France might benefit from a sort of electoral college since Paris, etc, elect their globalists. With Britain, it seems the royals really do influence most people. Ex, If William applauds the NHS, then they must be doing right. If the Queen encourages the vax, it can't be bad. The Queen would never lie to us. It doesn't seem to matter that England was once the cradle of freedom of speech, etc, the royals really do have a lot of influence despite the fact, they have never once shown their concern for the illegal invasion. But they will promote locking down and the vax. I can't believe people are not seeing the cognitive dissonance with a Monarchy. In fact Charles has gone along with people being arrested for protesting his coronation. There may be something deep in their DNA about being "subjects" not citizens.
Forwarded from World Council for Health
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It's finally here!! 🎉
Better Way Conference 2023
2-4 June 2023
8 Conversations | 70 Speakers
with Neil Oliver as Master of Ceremonies
Tune in live starting today at 2pm BST (two hours from now) or watch on demand from anywhere in the world whenever you like—as many times as you like! ☺️
🗝 BetterWayConference.org
Eight conversations:
1️⃣ From Big Pharma to Real Health
2️⃣ From Fake Foods to Food as Medicine
3️⃣ From AI & Transhumanism to Being Human
4️⃣ From Electrosmog to Nature’s Frequencies
5️⃣ From Climate Change to Nature Nurture
6️⃣ From Thought Control to Free Thought
7️⃣ From One Health to Our Health
8️⃣ From Scarcity to Abundance
70 speakers, including:
● Dr Pierre Kory
● Mattias Desmet
● Andrew Bridgen
● James Corbett
● Dr Jessica Rose
● Prof Norman Fenton
● Dr Tina Peers
● Patrick Holford
● Dan Astin-Gregory
● Derrick Broze
● Dr Zoë Harcombe
● Richard Vobes
● Robin Monotti
● Veronika Kyrylenko
● Vera Sharav
● Clive de Carle
● Dr Paul Marik
● Dr Sarah Myhill
● Deanna McLeod
● Dr Simon Goddek
● Ramiro Romani
● Dr Karina Acevedo-Whitehouse
● Rain Trozzi
● Dr Reiner Fuellmich
● Mark Devlin
● Jemma Cooper
● B. Love
● Dr Marc Cohen
● Dr Beverly Rubik
● Kim Witczak
● Dr Dietrich Klinghardt
● Dr Atsuo Yanagisawa
● Laura Aboli
● Dr Carrie Madej
● Dr Sabine Hazan
● David Fleming
● Reggie Littlejohn
● Dr Meryl Nass
● Darren Deojee
● Fahrie Hassan
● Dr Marivic Villa
● Prof Olle Johansson
● Kathleen Burke
● Feisal Mansoor
● William Keyte
● Jan Wellmann
● Dr André Leu
● Dr Jeremy Birnstingl
● Rev Dr Wai Ching Lee
● Alex Krainer
● Karen-Ruth Skolmli
● Stephanie Locricchio
● Melissa Ciummei
● Daisy Fretwell
● Rory Duff
● Debra Fry
● Dr Ramiz Ahmed-Man
● Howdie Mickoski
● Emma Sron
● Christof Plothe, DO
● Shabnam Palesa Mohamed
● Dr Mark Trozzi
● Dr Tess Lawrie
🗝 BetterWayConference.org
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Schätzung der Übersterblichkeit in Deutschland im Zeitraum 2020-2022
Christof Kuhbandner • Matthias Reitzner
Veröffentlicht: 23. Mai 2023
https://www.cureus.com/articles/149410-e#!/
Schätzung der Übersterblichkeit in Deutschland im Zeitraum 2020-2022
Christof Kuhbandner • Matthias Reitzner
Veröffentlicht: 23. Mai 2023
https://www.cureus.com/articles/149410-e#!/
Cureus
Estimation of Excess Mortality in Germany During 2020-2022
Background
This study estimates the burden of COVID-19 on mortality in Germany. It is expected that many people have died because of the new COVID-19 virus who otherwise would not have died. ...
This study estimates the burden of COVID-19 on mortality in Germany. It is expected that many people have died because of the new COVID-19 virus who otherwise would not have died. ...
...
The pathologist Prof. Arne Burkhardt is dead !
The cause of his unexpected death still seems unknown. Arne Burkhardt (1944-2023) did essential work to elucidate the criminal cabal and for justice and was a friend of all of us, a friend of humanity !
Dear friend, I would never forget you and I will always be grateful to you. Rest in peace !
Source 1 : Dr. Thomas Binder : https://t.me/DrThBi/1977
Source 2 : Prof. Stefan Hockertz : https://t.me/ProfHockertz/2441
The pathologist Prof. Arne Burkhardt is dead !
The cause of his unexpected death still seems unknown. Arne Burkhardt (1944-2023) did essential work to elucidate the criminal cabal and for justice and was a friend of all of us, a friend of humanity !
Dear friend, I would never forget you and I will always be grateful to you. Rest in peace !
Source 1 : Dr. Thomas Binder : https://t.me/DrThBi/1977
Source 2 : Prof. Stefan Hockertz : https://t.me/ProfHockertz/2441
Telegram
Dr. Thomas Binder, MD
I will always keep Prof. em. Arne Burkhardt (1944-2023) in my memories as one of the dearest, most intelligent, humblest, and most courageous people I had the privilege to know.
For his pioneering work in the pathology of the COVID "vaccines" he deserves…
For his pioneering work in the pathology of the COVID "vaccines" he deserves…
Forwarded from AUF1
Verstorben: Pathologe Prof. Arne Burkhardt (1944-2023)
Höchste Verdienste: Aufklärungsarbeit zur gefährlichen Covid-Gen-Injektionen
Mehrere Personen, die mit Prof. Burkhardt zusammengearbeitet haben, berichten am Freitagabend von seinem unerwarteten Tod.
Der Schweizer Rechtsanwalt Philipp Kruse schreibt: „Zum unerwarteten Tod des Pathologen Prof. Em. Arne Burkhardt, der sich höchste Verdienste bei der Aufklärung eines der grössten Menschheitsverbrechen erworben hat, der auch meinem Team im Rahmen unserer Strafanzeige gegen Swissmedic hervorragend geholfen und für die Hinterbliebenen von verstorbenen Impfopfern pro bono unglaublich wertvolle, umfassende Expertise bereitgestellt hat, und dem ich persönlich zu grösstem Dank verpflichtet bin.
Wir werden ihm ein ehrendes, dankbares Andenken bewahren, und wir werden seine Arbeiten vollenden!“
Das letzte Interview von Prof. Burkhardt mit AUF1 sehen Sie hier: https://auf1.tv/nachrichten-auf1/arne-burkhardt-ich-sehe-eine-uebersterblichkeit-aufgrund-der-mrna-impfung
Höchste Verdienste: Aufklärungsarbeit zur gefährlichen Covid-Gen-Injektionen
Mehrere Personen, die mit Prof. Burkhardt zusammengearbeitet haben, berichten am Freitagabend von seinem unerwarteten Tod.
Der Schweizer Rechtsanwalt Philipp Kruse schreibt: „Zum unerwarteten Tod des Pathologen Prof. Em. Arne Burkhardt, der sich höchste Verdienste bei der Aufklärung eines der grössten Menschheitsverbrechen erworben hat, der auch meinem Team im Rahmen unserer Strafanzeige gegen Swissmedic hervorragend geholfen und für die Hinterbliebenen von verstorbenen Impfopfern pro bono unglaublich wertvolle, umfassende Expertise bereitgestellt hat, und dem ich persönlich zu grösstem Dank verpflichtet bin.
Wir werden ihm ein ehrendes, dankbares Andenken bewahren, und wir werden seine Arbeiten vollenden!“
Das letzte Interview von Prof. Burkhardt mit AUF1 sehen Sie hier: https://auf1.tv/nachrichten-auf1/arne-burkhardt-ich-sehe-eine-uebersterblichkeit-aufgrund-der-mrna-impfung
Forwarded from RA/Avv. DDr. Renate Holzeisen
In Brüssel haben wir über so Vieles diskutiert … Arne war ein hoch intelligenter Mensch, der selbstlos pro bono in den vergangenen zwei Jahren unermüdlich und wesentlich an der wissenschaftlichen Aufklärung der durch die Covid-19-Injektionen verursachten Schäden beteiligt war. Er hat auch in “italienischen Fällen” plötzlich verstorbener junger Menschen gratis seine Gutachterleistungen erbracht und dafür auch Reisestrapazen auf sich genommen. In Anbetracht dessen was dieser großartige Mann und Wissenschaftler selbstlos im fortgeschrittenen Alter fortwährend geleistet hat, wäre es an der Zeit, dass sich viele Pathologenkollegen um eine ernsthafte, transparente und ergebnisoffene Aufklärung bemühten!
Alles andere wäre mehr denn je beschämend!
Alles andere wäre mehr denn je beschämend!
Forwarded from Schultz
DONT FORGET THE ORAL MICROBIOME
Immunologist at Tehran University of Medical Sciences
Maryam D
https://www.linkedin.com/posts/maryam-d-961420214_mdabrimmunol-immunology-oral-activity-7060498907520225281-gEwH
Oral microbiome and autoimmune diseases, friend or foe ?
https://europepmc.org/article/med/36949458
🌐 The human microbiome might be a major player in autoimmunity . Growing evidence has demonstrated that oral microbiota dysbiosis is actively involved in regulating the initiation and progression of an array of autoimmune diseases.
🌐 Oral microbiota is linked to a group of autoimmune diseases, namely Sjogren's syndrome (SS), systemic lupus erythematosus (SLE), Crohn's disease (CD), and rheumatoid arthritis (RA).
🌐 Mechanisms of autoimmunity triggered by dysbiotic changes and dysregulation of the immune system mediated by altered microbiome-host relationships.
🌐 The host-microbiome interaction may be influenced by several ecological changes (eating habits, aging, infection, among others) that may generate dysbiosis with the consequent activation of different local or systemic autoimmune mechanisms.
🌐 The dysregulation in the oral microbiome plays a crucial role in triggering and promoting autoimmune diseases via several mechanisms, including:⬇️⬇️ 👉🛑please see figure A
1️⃣ Autoantigens overproduction : the result of the breakdown of the extracellular matrix creating "remnant epitopes" that act as autoantigens or because of enzymatic modification of antigens (citrullination).
2️⃣ Microbial translocation : bacteria, their products or even products of immune activation against them, can migrate through the bloodstream to different organs leading to an alteration of the local inflammatory response and the production of autoantibodies.
3️⃣ Molecular mimicry : cross immune response against self-antigens induced by microbial epitopes similar in composition or structure.
4️⃣ Superantigens : Self or non-self-superantigens interact with the Vβ variable region of the TCR activating and causing T cell expansion. This is a low specificity recognition, which generates low-affinity antibodies that easily end up activating autoimmune mechanisms.
5️⃣ Dysregulation of checkpoints: alteration of the CTLA4 and PD-1 autoreactivity checkpoints in T cells, resulting in the loss of physiological modulation or regulation of the autoimmune response.
🌐 However, dysbiosis/infection and chronic inflammation could trigger autoimmunity by several mechanisms including bystander activation, dysregulation of toll-like receptors, amplification of autoimmunity by cytokines, epitope spreading, autoantigens complementarity, autoantigens overproduction, microbial translocation, molecular mimicry, superantigens, and activation,
or inhibition of receptors related to autoimmunity by microorganisms.
🌐 Thus, a comprehensive understanding of the relationship between oral microbiota dysbiosis and autoimmune diseases is critical for providing novel insights into the development of oral microbiota-based therapeutic approaches for combating these refractory diseases.
#immunology #oral #microbiome #autoimmunedisease
Immunologist at Tehran University of Medical Sciences
Maryam D
https://www.linkedin.com/posts/maryam-d-961420214_mdabrimmunol-immunology-oral-activity-7060498907520225281-gEwH
Oral microbiome and autoimmune diseases, friend or foe ?
https://europepmc.org/article/med/36949458
🌐 The human microbiome might be a major player in autoimmunity . Growing evidence has demonstrated that oral microbiota dysbiosis is actively involved in regulating the initiation and progression of an array of autoimmune diseases.
🌐 Oral microbiota is linked to a group of autoimmune diseases, namely Sjogren's syndrome (SS), systemic lupus erythematosus (SLE), Crohn's disease (CD), and rheumatoid arthritis (RA).
🌐 Mechanisms of autoimmunity triggered by dysbiotic changes and dysregulation of the immune system mediated by altered microbiome-host relationships.
🌐 The host-microbiome interaction may be influenced by several ecological changes (eating habits, aging, infection, among others) that may generate dysbiosis with the consequent activation of different local or systemic autoimmune mechanisms.
🌐 The dysregulation in the oral microbiome plays a crucial role in triggering and promoting autoimmune diseases via several mechanisms, including:⬇️⬇️ 👉🛑please see figure A
1️⃣ Autoantigens overproduction : the result of the breakdown of the extracellular matrix creating "remnant epitopes" that act as autoantigens or because of enzymatic modification of antigens (citrullination).
2️⃣ Microbial translocation : bacteria, their products or even products of immune activation against them, can migrate through the bloodstream to different organs leading to an alteration of the local inflammatory response and the production of autoantibodies.
3️⃣ Molecular mimicry : cross immune response against self-antigens induced by microbial epitopes similar in composition or structure.
4️⃣ Superantigens : Self or non-self-superantigens interact with the Vβ variable region of the TCR activating and causing T cell expansion. This is a low specificity recognition, which generates low-affinity antibodies that easily end up activating autoimmune mechanisms.
5️⃣ Dysregulation of checkpoints: alteration of the CTLA4 and PD-1 autoreactivity checkpoints in T cells, resulting in the loss of physiological modulation or regulation of the autoimmune response.
🌐 However, dysbiosis/infection and chronic inflammation could trigger autoimmunity by several mechanisms including bystander activation, dysregulation of toll-like receptors, amplification of autoimmunity by cytokines, epitope spreading, autoantigens complementarity, autoantigens overproduction, microbial translocation, molecular mimicry, superantigens, and activation,
or inhibition of receptors related to autoimmunity by microorganisms.
🌐 Thus, a comprehensive understanding of the relationship between oral microbiota dysbiosis and autoimmune diseases is critical for providing novel insights into the development of oral microbiota-based therapeutic approaches for combating these refractory diseases.
#immunology #oral #microbiome #autoimmunedisease
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Forwarded from Tony.I3.E.A
gender-study-.ajp.correction.pdf
424.6 KB
2020 Research Study: No benefits of gender surgery in improving mental health. Authors had to correct their initial conclusions which had said there was some benefit, when the actual data did not say that. Will MSM tell you this?
Correction to Bränström and Pachankis: 1 Aug 2020
https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2020.1778correction
Upon request, the authors reanalyzed the data to compare outcomes between individuals diagnosed with gender incongruence who had received gender-affirming surgical treatments and those diagnosed with gender incongruence who had not. While this comparison was performed retrospectively and was not part of the original research question given that several other factors may differ between the groups, the results demonstrated no advantage of surgery in relation to subsequent mood or anxiety disorder-related health care visits or prescriptions or hospitalizations following suicide attempts in that comparison.
Correction to Bränström and Pachankis: 1 Aug 2020
https://ajp.psychiatryonline.org/doi/10.1176/appi.ajp.2020.1778correction
Upon request, the authors reanalyzed the data to compare outcomes between individuals diagnosed with gender incongruence who had received gender-affirming surgical treatments and those diagnosed with gender incongruence who had not. While this comparison was performed retrospectively and was not part of the original research question given that several other factors may differ between the groups, the results demonstrated no advantage of surgery in relation to subsequent mood or anxiety disorder-related health care visits or prescriptions or hospitalizations following suicide attempts in that comparison.
Forwarded from Dr Tess Lawrie
It is simply no longer possible to believe in the journals, in the regulatory agencies and in official guidance.
"The journals are paid off, the FDA is paid off, the people on these regulatory panels who regulate these drugs are paid off. So, they are all paid off. And that is why a conflict of interest – it does not matter how big or how small – is a conflict. Once you have a conflict, you are conflicted and you cannot be honest.
Everyone should read the book [The Truth About the Drug Companies: How they deceive us and what to do about it] by Marcia Angell written in 2002. She was the editor of the New England Journal of Medicine at that time and she resigned because of her disgust with the system. She states:
'It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as editor of The New England Journal of Medicine.'
So this is somebody who really knows, who has seen it from the inside. This was in 2002. Seems like I was obviously still in the cradle because I had not seen the light."
— Dr. Paul Marik (second most published intensive care specialist in the world)
Join us:
🎟 BetterWayConference.org
"The journals are paid off, the FDA is paid off, the people on these regulatory panels who regulate these drugs are paid off. So, they are all paid off. And that is why a conflict of interest – it does not matter how big or how small – is a conflict. Once you have a conflict, you are conflicted and you cannot be honest.
Everyone should read the book [The Truth About the Drug Companies: How they deceive us and what to do about it] by Marcia Angell written in 2002. She was the editor of the New England Journal of Medicine at that time and she resigned because of her disgust with the system. She states:
'It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgment of trusted physicians or authoritative medical guidelines. I take no pleasure in this conclusion, which I reached slowly and reluctantly over my two decades as editor of The New England Journal of Medicine.'
So this is somebody who really knows, who has seen it from the inside. This was in 2002. Seems like I was obviously still in the cradle because I had not seen the light."
— Dr. Paul Marik (second most published intensive care specialist in the world)
Join us:
🎟 BetterWayConference.org