12-All of the following statements about anti-cough remedies are true, EXCEPT:
Anonymous Quiz
85%
Cough suppressants are called antiemetics
3%
Dry irritative cough should be suppressed
8%
Guaiacol is a stimulant expectorant
5%
Codeine can be complicated by constipation.
The first line in treatment of acute attack of bronchial asthma is the quick relief medication:
Anonymous Quiz
90%
Inhaled B2 agonist
5%
Muscarinic antagonist inhalation
2%
Oral theophylline
2%
Cromolyn sodium orally
The following drugs can be used in treatment of bronchial asthma EXCEPT:
Anonymous Quiz
2%
Aminophylline
7%
Salbutamol
26%
Ketotifen
65%
Carbachol
β€1
Concerning the inhaled asthma reliever salbutamol, which of the following is INCORRECT
Anonymous Quiz
16%
It stimulate beta-2 adrenoceptors
77%
It may produce bradycardia
2%
It relax bronchial smooth muscle
5%
It is used by inhalation or oral
Terbutaline specifically stimulates:
Anonymous Quiz
2%
Alpha receptors
2%
Alpha 2 receptors
9%
Beta receptors
87%
Beta 2 receptors
The following drugs are useful in management of asthma EXCEPT:
Anonymous Quiz
0%
Montelukast
76%
Leukotreine
12%
Prednisolone
12%
Ipratropium
Fluticasone by inhalation is useful in long-term control of bronchial asthma by acting as:
Anonymous Quiz
0%
Anti-leukotriene
2%
Anti-histamine
95%
Anti-inflammatory corticosteroid
2%
Mast cell stabilizer
Theophylline produce a bronchodilator effect through:
Anonymous Quiz
4%
Stimulation of Γ2-receptors
8%
Decrease c-AMP level
2%
Blockade of M1-receptors
86%
Inhibit PDE enzyme
Side effects of salbutamol include which of the following:
Anonymous Quiz
81%
Tachycardia
13%
Bradycardia
6%
Vomiting
0%
CNS depression
The following drug is a quick relief medication for acute bronchial asthma
Anonymous Quiz
98%
Inhaled salbutamol
0%
Montelukast
0%
Nedocromil by inhalation
2%
Oral theophylline
Long-term control medications of chronic bronchial asthma include the following drugs EXCEPT:
Anonymous Quiz
0%
Selective long-acting 32-agonists (LABA) as salmeterol
4%
Slow release theophylline
13%
Inhaled corticosteroids as budesonide
83%
B-adrenergic antagonists as pindolol
Adrenergic agonists clearly play a role in managing some patients with asthma,whether for prophylaxis .Which of the following drugs is classified as an adrenergic agonist, but has no physiologically relevant effects on airway smooth muscle tone?
Anonymous Quiz
4%
Albuterol
69%
Norepinephrine
16%
Salmeterol
10%
Terbutaline
An elderly man with COPD is being managed with several drugs, one of which is inhaled ipratropium. Which of the following is the main mechanism that accounts for the beneficial effects of this drug?
Anonymous Quiz
81%
Blocks of an endogenous bronchoconstrictor mediator
11%
Inhibits CAMP breakdown via phosphodiesterase inhibition
3%
Prevents antigen-antibody reactions that lead to mast cell mediator release
5%
Stimulates ventilatory rates (CNS effect in brain's medulla
A 16-year-old girl treated for asthma develops skeletal muscle tremors that are drug-induced. Which of the following was the most likely cause?
Anonymous Quiz
92%
Salbutamol
5%
Beclomethasone
0%
Cromolyn
3%
Ipratropium
A 26-year-old patient with asthma is being treated with montelukast. Which of the following is the main mechanism by which this drug works?
Anonymous Quiz
90%
Blocks the proinflammatory effects of certain arachidonic acid metabolites
2%
Enhances release of epinephrine from the adrenal (suprarenal) medulla
2%
Increases airway αΊ-adrenergic receptor responsiveness to endogenous norepinephrine
5%
Inhibits cAMP breakdown via phosphodiesterase inhibition
An elderly man, in obvious respiratory distress due to exacerbation of his
emphysema and chronic bronchitis to be administered by respiratory therapist, is N-acetylcysteine. Which of the following is main action or purpose of this drug?
emphysema and chronic bronchitis to be administered by respiratory therapist, is N-acetylcysteine. Which of the following is main action or purpose of this drug?
Anonymous Quiz
11%
Block receptors for the cysteinyl leukotrienes
0%
Inhibit metabolic inactivation of epinephrine or αΊ2-agonsits that were administered
6%
Inhibit leukotriene synthesis
83%
Thin airway mucus secretions for easier removal by suctioning or postural drainage
A woman with asthma has what is described as "aspirin hypersensitivity" and experiences severe bronchospasm in response to small doses of the drug.Which of the following is the most likely mechanism by which of the aspirin provokes her pulmonary problems?
Anonymous Quiz
58%
Stimulates synthesis of leukotrienes
8%
Induces formation of antibodies directed against the salicylate on airway mast cells
14%
Induces hypersensitivity of Hβ receptors on airway smooth muscles.
19%
Induces hypersensitivity of muscarinic receptors on airway smooth muscles
β€1
patient suffers from asthmatics,large parenteral doses of a selective αΊ2 agonist fail to dilate the airways adequately,they cause dangerous degrees of tachycardia Which of the following approaches is to restore the bronchodilator of the adrenergic drug?
Anonymous Quiz
11%
Add inhaled cromolyn
69%
Give a parenteral corticosteroid
9%
Give parenteral diphenhydramine
11%
Switch to epinephrine
Muscarinic agonists such as pilocarpine, and αΊ blockers,are among the drugs used to manage a case of glaucoma,they also share properties that are relevant to patients with asthma. Which of the following statements summarizes best what that relevance is?
Anonymous Quiz
66%
Contraindicated, or pose great risks, for people with asthma
3%
Degranulate mast celis, cause bronchoconstriction
17%
Tend to raise intraocular pressure in patients who have both glaucoma and asthma
14%
Useful for acute asthma, not for ambulatory patients
A 23-year-old woman is using a salbutamol inhaler for frequent acute episodes of asthma and describes symptoms that she ascribes to salbutamol. Which of the following is NOT a recognized action of salbutamol?
Anonymous Quiz
74%
Diuretic effect
3%
Positive inotropic effect
9%
Skeletal muscle tremor
14%
Smooth muscle relaxation