How do effector T-cells differ from naive T-cells?
Anonymous Quiz
29%
They can be triggered without the need for antigen-presenting cell
54%
They can be triggered without the need for co-stimulatory malestule
8%
They can be triggered without the need for CD4 or CD8 molecules
8%
They can be triggered without the need for signal transmission by CD3
Regarding the vesicular pathogens, which statement is CORRECT?
Anonymous Quiz
22%
They are degraded in the cytoplasm.
4%
Their peptides bind to MHC I molecules
9%
They are presented to CDB-T cells.
65%
They include intracellular bacteria.
Which cytokine inhibits the development of Th2 cells
Anonymous Quiz
76%
IFN-Y
4%
IL-6
8%
IL-4
12%
TNF-a
The main function of the humoral immune response is:
Anonymous Quiz
8%
Destruction of intracellular pathogens
75%
Destruction of extracellular pathogens
17%
Helping other cells of the immune system
0%
Production of Cytokines
A surface molecule on B cells essential for antigen presentation is:
Anonymous Quiz
30%
B cell receptor (BCR)
9%
CD40
61%
MHCII
0%
Immunoglobulin
Activation of naΓ―ve mature B cells requires the following EXCEPT:
Anonymous Quiz
10%
Surface antibody contact with antigen
10%
T cell cytokine stimulation
14%
8 cell CD40 interaction with T cell CD40
67%
Antigen presentation to T cell via class I MHC
The second signal in activation of naΓ―ve B cells includes all of the following EXCEPT:
Anonymous Quiz
37%
Antigen binding to B cell receptor
5%
Activated helper T cells
37%
Engulfment and degradation of the bound antigen by B cell
21%
Peptide presentation on the B cell surface in association with MHC II
The role of macrophages during antibody formation is:
Anonymous Quiz
11%
Production of cytokines
84%
Processing and presentation of antigens to CD4 T helper cells
0%
Activation of CD8 T cytotoxic cells
5%
Promotion of development of Thi cells
Which of the following has an effect on humoral immunity?
Anonymous Quiz
11%
Activation of cytotoxic CD8 T cells
11%
Lysis of virus infected cells
74%
Processing and presentation of antigen to T helper cells
5%
Activation of NK cells
All of the following statements about memory cells are true EXCEPT:
Anonymous Quiz
6%
They are produced in response to thymus-dependent antigens
6%
They are responsible for immunological memory
89%
They are short-lived cells
0%
They are produced following the primary immune response
Thymus Independent (TI) antigens
Anonymous Quiz
6%
Can stimulate B cells through T cell help
89%
Do not produce memory cells.
6%
Can stimulate immunoglobulin class switching
0%
Can only induce the production of IgG
The heavy chain of immunoglobulin consists of:
Anonymous Quiz
10%
One variable and two constant domains
20%
Two variable and one constant domain
10%
One variable one constant domain
60%
One variable and three or four constant domains
Opsonization depend on presence of the following structures on surface of phagocytic cells:
Anonymous Quiz
5%
Foreceptors
32%
C3b receptors
0%
CBCR
47%
a&b
16%
a&c
Regarding ADCC, all the following are true EXCEPT:
Anonymous Quiz
53%
it occurs through apoptosis of the target cell
0%
It may be mediated by NK cells
21%
It is a cytotoxic reaction against an antibody-coated cell
26%
It is an example of enhancing of innate immunity by specific Immunity
Which of the following cells is involved in ADCC:
Anonymous Quiz
5%
CD4 cell
0%
CD8 cell
16%
Mature B cell
79%
Natural killer (NK) cell
All the following statements are true about IgG EXCEPT:
Anonymous Quiz
58%
It is an example of enhancing of innate immunity by specific Immunity
16%
it can pass the placenta barrier to the fetal circulation
11%
It is the major antibody of the secondary immune response
16%
Anti-Rh antibodies are of the IgG glass