42. The following statement is not true about retinoblastoma:
Anonymous Quiz
10%
a) An autosomal dominant inherited cancer syndrome
60%
b) Characterized by defects in DNA repair & genomic stability
30%
c) One defective allele of RB gene is inherited
0%
d) Patients also show increased risk of developing other cancer malignancies
62. What is the name of the phenomenon mediated by the selectin family?
Anonymous Quiz
0%
a) Chemotaxis
9%
b) Pavementing
0%
c) Emigration
91%
d) Rolling
6. In mechanism of metaplasia, the following is true:
Anonymous Quiz
10%
a) A neoplastic process that maintain the integrity of the basement membrane
10%
b) Results from change in the phenotype of an already differentiated cell type
50%
c) Results from reprogamming of stem cells known to exist in normal tissue
30%
d) Can occur physiological or pathological
19) The major factors predisposing to thrombogenesis include all of the following except:
Anonymous Quiz
18%
a) Altered blood flow
0%
b) Endothelial injury
82%
c) Pattern of blood flow
0%
d) Hypercoagulability of blood
9) Which of the following statement regarding disseminated intravascular coagulation (DIC) is FALSE?
Anonymous Quiz
0%
a) Multiple thrombi develop in the microcirculation
0%
b) Rapid consumption of platelets, prothrombin & fibrinogen occurs
67%
c) Bleeding diathesis is solely due to thrombocytopenia
33%
d) Fibronogen degradation products (FDPs) increase due to rapid fibrinolysis.
44. A common site for hamartoma:
Anonymous Quiz
54%
a) Lung
15%
b) Duodenum
23%
c) Breast
8%
d) Urinary bladder
15. In acute inflammation, which is the correct sequence of events with regard to vascular flow and caliber?
Anonymous Quiz
10%
a) Vasodilation, margination, stasis, vasoconstriction
0%
b) Vasoconstriction, stasis, margination, vasodilation
90%
d) Vasoconstriction, vasodilation, stasis, margination
0%
e) Vasodilation, vasoconstriction, stasis, margination
0%
c) Vasodilation, stasis, vasoconstriction, marginaiton
13) Which of the following statements are TRUE?
Anonymous Quiz
9%
a)Amniotic fluid embolism occurs during labour due to tear in the placental membrane.
0%
b) Mortality rate of amniotic fluid embolism is high.
0%
c) Patients with amniotic fluid embolism develop acute pulmonary oedema, RDS & DIC.
91%
d) All of the above
4) Endothelial cells can be activated (develop procoagulant properties) by:
Anonymous Quiz
25%
a) Cytokines
8%
b) Hemodynamic factors
0%
c) Plasma constituents
67%
d) All of the above
46. Chemotatic factors may include the following except:
Anonymous Quiz
0%
a) Leukotriene B4
8%
b) Chemokine
92%
c) Nitric oxide
0%
d) Bacterial products
47. Which of the following is true about fibrin?
Anonymous Quiz
0%
a) Deposition of fibrin in inflammatory conditions is known as fibrosis
67%
b) Fibrin plays important functions in inflammation & repair
8%
c) Cellulitis is characterized by excess fibrin deposition
25%
d) All of the above
45. Which of the following is an effect of chemical mediators?
Anonymous Quiz
0%
a) Increased vascular permeability.
0%
b) Chemotaxis
0%
c) Fever
100%
d) All of the above
50. One of the following is associated with marked tissue necrosis:
Anonymous Quiz
0%
a) Silicosis
6%
b) Foreign body granuloma
6%
c) Sarcoidosis
88%
d) Tuberculosis.
3) Transudation may occur due to the following EXCEPT:
Anonymous Quiz
25%
a) Increased intravascular hydrostatic pressure.
50%
b) Increased intravascular oncotic pressure.
0%
c) Lymphatic obstruction
25%
d) Renal salt & water retention
58. Guardian of the genome is:
Anonymous Quiz
7%
a) RB gene
87%
b) P53 gene
0%
c) MYC gene
7%
d) Bcl2
22) The most reliable post mortem feature of left sided cardiac failure is:
Anonymous Quiz
8%
a) Systemic venous congestion
92%
b) Chronic venous congestion of lungs
0%
c) Enlargement of spleen and liver
0%
d) Oedematous ankles
50. Aflatoxins can cause:
Anonymous Quiz
0%
a) Lung carcinoma
14%
b) Mesothelioma
86%
c) Hepatic carcinoma
0%
d) Skin cancer
65. Immunohistochemistry is a powerful tool in diagnosing:
Anonymous Quiz
0%
a) High stage tumors
8%
b) Low grade tumors
69%
c) Poorly differentiated tumors
23%
d) Metastatic tumors
51. Bcl2 is considered:
Anonymous Quiz
0%
a) Proto-oncogene
7%
b) Oncogene
14%
c) Tumor suppressor gene
79%
d) Anti-apoptotic gene
53. Para-neoplastic syndromes commonly seen with:
Anonymous Quiz
54%
a) Lung carcinoma
31%
b) Hepatocellular carcinoma
15%
c) Breast carcinoma
0%
d) Colonic carcinoma