39. What type of leukocyte actively participates in acute inflammatory processes and contains myeloperoxidase within its primary (azurophilic) granules and alkaline phosphatase in its secondary (specific) granules?
Anonymous Quiz
92%
a) Neutrophils
8%
b) Eosinophils
0%
c) Monocytes
0%
d) Lymphocytes
0%
e) Plasma cells
13. Which of the following is not correct regarding carcinoma in situ:
Anonymous Quiz
7%
a) Pre-invasive stage of carcinoma
27%
b) Characterized by severe dysplasia without invasion of the basement membrane
60%
c) Common sites include liver and kidney
7%
d) Cells are pleomorphic and hyperchromatic with increased mitoses
. Which of these is not a clinical feature of inflammation?
Anonymous Quiz
6%
a) redness
94%
b) necrosis
0%
c) pain
0%
d) heat
In acute inflammation chemotactic agents cause endothelial cell activation by all of the following except:
Anonymous Quiz
23%
a) Activation of oxidative burst
15%
b) De-granulation and secretion of enzymes
0%
c) Production of arachidonic acid metabolite
62%
d) Inhibition of cellular adhesion
0%
e) Modulation of leukocyte adhesion
18) Shock is a circulatory disturbance characterized
Anonymous Quiz
0%
a) Increased blood pressure
86%
b) Decreased volume of circulating blood
0%
c) Elevated body temperature
14%
d) Decreased volume of interstitial fluid
. Chemotatic factors may include the following except:
a) Leukotriene B4 b) Chemokine c) Nitric oxide d) Bacterial products
a) Leukotriene B4 b) Chemokine c) Nitric oxide d) Bacterial products
Anonymous Quiz
12%
a) Leukotriene B4
0%
b) Chemokine
82%
c) Nitric oxide
6%
d) Bacterial products
11) Which of following statements are FALSE?
Anonymous Quiz
79%
a) Embolic obstruction of small or medium sized arteries results in pulmonary infarct
7%
b) Multiple PEs can lead to development of pulmonary hypertension & chronic right heart failure.
14%
c) 60-80% of PEs are clinically silent
0%
d) Natural course of PE includes resolution & organization of the emboli.
43. A benign tumor known to be precancerous:
Anonymous Quiz
16%
a) Leiomyoma
16%
b) Squamous cell papilloma
68%
c) Villous bladder papilloma
0%
d) Fibroadenoma
51. Which of the following is not a feature of acute inflammation?
.
.
Anonymous Quiz
88%
a) Persistent vasoconstriction.
0%
b) Vasodilatation
6%
c) Increased vascular permeability.
6%
d) Vascular stasis.
0%
e) Emigration of leucocytes
35. During the early stages of the inflammatory response, histamine induced increased vascular permeability is most likely to occur in
Anonymous Quiz
5%
a) Arteries
24%
b) Pre-capillary arterioles
10%
c) Capillaries
57%
d) Post-capillary venules
5%
e) Veins
12) Common risk factors for arterial thrombo-emboli include the following EXCEPT:
Anonymous Quiz
10%
a) Acute myocardial infarction
40%
b) Paradoxical embolism from venous thrombi
30%
c) Rheumatic heart disease
20%
d) Cardiomyopathy
67. The erbB2 is mutated in breast cancer by which of the following mechanisms?
Anonymous Quiz
50%
a) Point mutation
19%
b) Chromosomal translocation
27%
c) Gene amplification
4%
d) Telomerase activation
66. Mutations of RAS gene is common in:
Anonymous Quiz
74%
a) Thyroid cancer
9%
b) Breast cancer
0%
c) Lung cancer
17%
d) Neuroblastoma
👍1
5) A cholecystectomy specimen is examined fresh in the laboratory. It shows a large impacted gallstone in the neck. Fundus of the gallbladder shows engorgement of blood vessels on external surface. This is most likely due to:
Anonymous Quiz
10%
a) A malignant process
5%
b) Hyperemia
75%
c) Congestion due to obstruction to outflow of blood
10%
d) Chronic inflammation
41. By definition, granulomas are composed of:
Anonymous Quiz
0%
a) Cholesterol clefts
0%
b) Collagen
25%
c) Endothelial cells and fibroblasts
71%
d) Epithelioid cells
4%
e) Hemosiderin-laden macrophages
17. Chronic inflammation is characterized by all of the below except:
Anonymous Quiz
12%
a) Tissue destruction
69%
b) Marked edema
4%
c) Fibrosis
15%
d) Increased tissue concentration of lymphocytes