As regard peptides arising in the cytosol or in the vesicular system:
Anonymous Quiz
75%
Cytosol peptides are carried on MHC I molecules
13%
Vesicular peptides are carried on MHC I molecules
6%
Cytosol peptides are presented to helper T cells
6%
Vesicular peptides are presented to cytotoxic T cells
The role of T cell in the immune response includes:
Anonymous Quiz
88%
Recognition of epitopes presented with MHC molecules on cell surfaces
0%
Antigen presentation
0%
Phagocytosis
13%
Complement activation
During the process of antigen recognition, the second signal needed for T cell activation is delivered when:
Anonymous Quiz
24%
CD40 ligand binds to CD40 molecule
6%
CD4 binds to MHCII molecule
6%
CD8 binds to MHCI molecule
65%
CD28 binds to B7 molecule
Which statement about the primary immune response is Not true
Anonymous Quiz
13%
Requires two signals for activation Tealis
0%
Produces effector T cells
13%
Produces memory T cells
73%
Produces naive T cells
One of the following is a pro-inflammatory cytokine:
Anonymous Quiz
14%
TGF - a
64%
TNF - ß
5%
IL 4
18%
IL 5
Th1 cells are characterized by:
Anonymous Quiz
6%
They produce IL-4
6%
They are activated by IL-4
6%
Their development is promoted by IL-4
81%
Their development is inhibited by IL 4
All of the following statements about Th1 cells are true EXCEPT:
Anonymous Quiz
15%
They produce IL-2
8%
Their development is promoted by IFN-y
15%
Their development is inhibited by IL-4 and IL-10
62%
They produce TGF-B
Development of Th1 cells is promoted by:
Anonymous Quiz
6%
IL12
65%
IFN-y
6%
Large doses of antigen
24%
All of the above
Development of Th2 cells is promoted by:
Anonymous Quiz
40%
IL-4
5%
Small doses of antigen
45%
Both of the above
10%
Neither of the above
Th2 cells are involved in:
Anonymous Quiz
6%
Antigen processing
88%
Helping B-cells to respond to T-dependent antigen
6%
Mucosal immunity
0%
Secretion of IL-1
The primary role of Th2 cells is to
Anonymous Quiz
6%
Function as T killer cells
6%
Activate NK cells
88%
Activate B cells
0%
Activate macrophages
All of the following statements about Th2 cells are true EXCEPT:
Anonymous Quiz
17%
They produce IL-3, 4, 5 and 6
8%
Their development is inhibited by IFN-y
0%
Their development is promoted by IL-4
75%
They promote cell-mediated immunity
Type I interferon leads to better killing of virus-infected cells due to:
Anonymous Quiz
11%
Increased expression of MHC | molecules
16%
Increased activity of NK cells
58%
Both
16%
Neither
The cytokine which increases the expression of MHC II on APCs is:
Anonymous Quiz
63%
IFN-Y
6%
TNF-B
0%
IFN-a
0%
IL-5
31%
IL-4
All the following statements regarding IFN-y are true EXCEPT:
Anonymous Quiz
0%
it activates macrophages
0%
It activates NK cells
5%
It promates development of Th1 celis
95%
It is produced mainly by Th2 cells