Which of the following cells is involved in ADCC:
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5%
CD4 cell
0%
CD8 cell
16%
Mature B cell
79%
Natural killer (NK) cell
All the following statements are true about IgG EXCEPT:
Anonymous Quiz
58%
It is an example of enhancing of innate immunity by specific Immunity
16%
it can pass the placenta barrier to the fetal circulation
11%
It is the major antibody of the secondary immune response
16%
Anti-Rh antibodies are of the IgG glass
All of the following statenments concerning IgG are true EXCEPT:
Anonymous Quiz
82%
it is the major antibody of the primary immune response
0%
It is composed of a single basic unit (monomer
12%
It is the only antibody that can cross the placenta
6%
it is the principal isotype in blood and extracellular fluids
The major immunoglobulin present in the human serum is:
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9%
igA
0%
IgD
4%
IgE
78%
igG
9%
IgM
The only immunoglobulin class which can cross the placenta is:
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5%
IgM
0%
IgA
86%
IgG
5%
IgD
5%
IgE
The only immunoglobulin to thymus independent (TI) antigen is:
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70%
IgM
5%
IgA
0%
IgG
10%
IgD
15%
IgE
All of the following statements concerning IgM are true EXCEPT:
Anonymous Quiz
60%
It is present in blood and extracellular fluids
0%
it is the major antibody in the primary immune response
10%
It cannot cross the placental barrier
30%
It is the most efficient complement fixing antibody
Which of the following statements about IgM is true:
Anonymous Quiz
5%
It is the secretory antibody
90%
It is important in the first few days of the primary immune response
5%
It is the smallest of the immunoglobulin molecules
0%
It is involved in allergic reactions
Which is the most efficient complement-fixing antibody?
Anonymous Quiz
73%
IgM
19%
igG
0%
IgE
8%
Secretory IgA
0%
Serum IgA
Diagnosis of Infection in the newborn depends on the detection of:
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13%
IgG
71%
IgM
3%
IgE
3%
Secretory IgA
10%
Serum IgA
IgA is characterized by the following EXCEPT:
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11%
it may exist in monomaniac or dimmer form
7%
It provides immunity at mucosal surface
7%
It is protected from proteolytic cleavage by secretory piece
75%
it can cross the placental barrier.
The secretory component of IgA is synthesized by:
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79%
Local mucosal cells
14%
B-cells
0%
Endothelial cells
7%
Plasma cells
The main antibody in secretions protecting outer surfaces of mucosal membranes are:
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10%
IgA and IgE
3%
IgE and IgD
7%
IgM and IgG
69%
IgA
10%
IgA and IgM
The following immunoglobulin provides local immunity at the mucosal surfaces:
Anonymous Quiz
3%
IgM
0%
IgD
94%
IgA
3%
IgG
0%
IgE
All of the following are examples of how acquired immunity can help innate immunity EXCEPT:
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8%
Macrophage activation by Th1 celis
50%
Antigen presentation to T cells
17%
NK cell activation by IL-2 to give LAK cells
8%
Antibody-mediated opsonization
17%
ADCC
Immunoglobulin class switching is mediated by a change in;
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76%
Constant domains of heavy chains
4%
Constant domains of light chains
12%
Variable domain of heavy chain
8%
Constant domain of both heavy and light chain
Regarding the primary immune response:
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12%
There is a very short induction (lag) period
84%
Immunoglobulins produced are mainly of IgM class
4%
Memory cells are the main effector cells
0%
The induced antibody level is very high