Which of the following effects of salicylates can be mediated through inhibition of
Kallikrein enzymes?
Kallikrein enzymes?
Anonymous Quiz
23%
Antipyretic effect
69%
Anti-rheumatic effect
8%
Keratolytic effect
0%
Fungistatic effect
Which of the following antiepileptic drugs is hepatic microsomal enzyme inhibitor?
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Anonymous Quiz
0%
Ethosuximide
36%
Sodium valproate
36%
Phenytoin
27%
Phenobarbitone
Co-analgesics include which of the following?
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Anonymous Quiz
38%
Codeine
38%
Gabapentin
25%
Aspirin
0%
Oxycodone
Which of the following adverse effects is expected to occur when long-term lithium
Anonymous Quiz
54%
Hypothyroidism
23%
Aggression and violence
8%
Mood disorders
15%
Tardive dyskinesia
Paracetamol can produce the following side effect as overdose toxicity sign:
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Anonymous Quiz
0%
Gastric irritation
6%
Bronchospasm
0%
ο»Ώο»Ώο»Ώο»Ώο»ΏBleeding tendency
94%
Hepatotoxicity
Toxicity of tricyclic antidepressants is best managed by:
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Anonymous Quiz
64%
ο»Ώο»ΏNa HCo3
7%
Atropine
29%
Flumazenil
0%
Morphine
Which of the following is CORRECT regarding the pharmacokinetics of Salicylates?
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Anonymous Quiz
100%
Highly bound to plasma protein
0%
ο»Ώο»Ώο»ΏCan't pass intact meninges
0%
Absorbed more from stomach
0%
Excreted mainly unchanged in the urine
In a rehabilitation center for addiction, clonidine is used to:
a)
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a)
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Anonymous Quiz
77%
Reduce hyperalgesia during withdrawal symptoms.
15%
Block mu opioid receptors.
0%
Boost the activity of methadone.
8%
Replace morphine.
Compared to morphine, meperidine has:
Anonymous Quiz
0%
better analgesic activity
0%
More antitussive effect
92%
Increased safety regarding respiratory depression
8%
No interaction with MAOls.
A young boy who has been treated for epilepsy for a year is referred to a dentist for evaluation of gingival hyperplasia. Which of the following antiepileptic drugs was the most likely cause of this oral pathology?
Anonymous Quiz
0%
ο»Ώο»Ώο»ΏGabapentinο»Ώο»Ώο»Ώο»Ώο»Ώο»Ώ
10%
Valproic acid
10%
Clonazepam
80%
Phenytoin
For an epileptic fit that lasted more than 10 minutes and did not respond to alprazolam, which of the following would be given next?
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Anonymous Quiz
20%
Midazolam
10%
Propofol
30%
Carbamazepine
40%
Phenytoin
which or the following is a first step in analgesic ladder
Anonymous Quiz
69%
Acetaminophen
23%
Fentanyl
8%
Codeine
0%
Methadone
Select the psychotropic drug having a narrow safety margin, necessitating plasma concentration monitoring:
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Anonymous Quiz
31%
Chlorpromazine
8%
Buspirone
62%
Lithium carbonate
0%
Fluoxetine
The nonselective MAO inhibitors are not used clinically as antidepressants because of their:
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Anonymous Quiz
0%
Low antidepressant efficacy
15%
Higher toxicity
38%
Potential to interact with many foods and drugs
46%
Both 'B' and 'C' are correct
Which of the following effects of salicylates on blood is an idiosyncratic reaction?
Anonymous Quiz
0%
Hypoprothrombinemia
8%
Decrease elevated erythrocytic sedimentation rate
75%
Hemolysis
17%
Decrease platelet aggregation
Which one of the following antidepressant having both high sedative and high anticholinergic activity??
Anonymous Quiz
14%
Imipramine
71%
Amitriptyline
14%
Fluoxetine
0%
Trazodone
Exercise with eating behavior modification should be the main line of management of obese patients with BMI:
Anonymous Quiz
42%
30
25%
27
25%
40
8%
25
The following drug is a methylanthine derivative and used in treatment of Intermittent claudication
Anonymous Quiz
0%
Atropine
56%
Pentoxifylline
33%
Chlorpromazine
11%
Fentanyl
Antiepileptic drug that is used in treatment of ventricular arrhythmia with heart block:
Anonymous Quiz
8%
Valproate
8%
Ethothuximide
8%
Lamotrigin
77%
Phenytoin
Concerning the proposed mechanisms of action of antidepressant drugs, which statement is accurate?
Anonymous Quiz
7%
a) Bupropion is one of the selective serotonin reuptake inhibitors.
86%
Chronic treatment with tricyclic antidepressants leads to significant sedative effect
0%
TCA are preferred in cardiac patients.
7%
Nefazodone one of the potent MAO inhibitors