Select the psychotropic drug having a narrow safety margin, necessitating plasma concentration monitoring:
Anonymous Quiz
31%
Chlorpromazine
8%
Buspirone
62%
Lithium carbonate
0%
Fluoxetine
The nonselective MAO inhibitors are not used clinically as antidepressants because of their:
Anonymous Quiz
0%
Low antidepressant efficacy
15%
Higher toxicity
38%
Potential to interact with many foods and drugs
46%
Both 'B' and 'C' are correct
Which of the following effects of salicylates on blood is an idiosyncratic reaction?
Anonymous Quiz
0%
Hypoprothrombinemia
8%
Decrease elevated erythrocytic sedimentation rate
75%
Hemolysis
17%
Decrease platelet aggregation
Which one of the following antidepressant having both high sedative and high anticholinergic activity??
Anonymous Quiz
14%
Imipramine
71%
Amitriptyline
14%
Fluoxetine
0%
Trazodone
Exercise with eating behavior modification should be the main line of management of obese patients with BMI:
Anonymous Quiz
42%
30
25%
27
25%
40
8%
25
The following drug is a methylanthine derivative and used in treatment of Intermittent claudication
Anonymous Quiz
0%
Atropine
56%
Pentoxifylline
33%
Chlorpromazine
11%
Fentanyl
Antiepileptic drug that is used in treatment of ventricular arrhythmia with heart block:
Anonymous Quiz
8%
Valproate
8%
Ethothuximide
8%
Lamotrigin
77%
Phenytoin
Concerning the proposed mechanisms of action of antidepressant drugs, which statement is accurate?
Anonymous Quiz
7%
a) Bupropion is one of the selective serotonin reuptake inhibitors.
86%
Chronic treatment with tricyclic antidepressants leads to significant sedative effect
0%
TCA are preferred in cardiac patients.
7%
Nefazodone one of the potent MAO inhibitors
A female patient is experiencing a depressive episode as part of her bipolar illness. She is been prescribed fluoxetine as monotherapy. Which of the following is anticipated to occur?
Anonymous Quiz
46%
Relief of depression.
4%
Aggravation of depression.
38%
Provocation of acute manic attack.
11%
Reduction of the dose of lithium carbonate
Salicylates can produce bronchial asthma through increase production of:
Anonymous Quiz
16%
Kinins
0%
Interferon
16%
Thromboxane A2
68%
Leukotrienes
The following action of diclofenac augments its anti-inflammatory action:
Anonymous Quiz
23%
Blockade leukotriene receptors
15%
Increase blood cortisol level
38%
Incorporate Arachidonic acid into Triglycerides
23%
Induce cyclooxygenase Il enzyme
1. Which of the following is TRUE about adult polycystic kidney?
Anonymous Quiz
23%
a) Kidney shows smooth outer surface.
15%
b) It is due to autosomal recessive anomaly.
0%
c) The cysts are communicating with renal pelvis.
62%
d) It is due to failure of fusion of convoluted and collecting tubules.
👍1
2. Acute diffuse proliferative glomerulonephritis is due to:
. .
. .
Anonymous Quiz
12%
a) Blood-borne infection.
12%
b) Ascending infection
65%
c) Deposition of immune complexes in the glomeruli.
12%
d) Autoimmune reaction
3. Epithelial crescents are characteristic of:
.
.
Anonymous Quiz
6%
a) Acute diffuse proliferative glomerulonephritis.
83%
b) Rapidly progressive glomerulonephritis.
11%
c) Membranous glomerulonephritis
0%
d) Minimal change glomerulonephritis 19/59
4. Fusion of the foot processes of the podocytes is characteristic of:
.
.
Anonymous Quiz
11%
a) Acute diffuse proliferative GN.
0%
b) Rapidly progressive GN.
11%
c) Membranoproliferative GN.
79%
d) Minimal change disease
5. Gross features of the kidneys in chronic glomerulonephritis include all EXCEPT:
. .
. .
Anonymous Quiz
17%
a) Both kidneys are contracted
72%
b) Contraction of the kidneys is asymmetrical.
6%
c) Outer surface is granular
6%
d) Loss of differentiation between cortex and medulla.
6. The most common cause of nephrotic syndrome in adult is:
.
.
Anonymous Quiz
28%
a) Acute diffuse proliferative.
6%
b) Minimal change disease.
61%
c) Membranous nephropathy
6%
d) Rapidly progressive GN.
7. In acute ischemic tubular necrosis:Except
.
.
Anonymous Quiz
18%
a) The kidneys are swollen and Pale
41%
b) The tubular necrosis is diffuse.
24%
c) The tubules show disruption of basement membrane.
18%
d) The distal tubules show casts.
8. Factors predisposing to pyelonephritis include all EXCED
.
. . .
.
. . .
Anonymous Quiz
11%
a) Urinary tract obstruction
11%
b) Urinary tract instrumentation
79%
c) Hypertension
0%
d) Diabetes