. The first vascular response to injury is:
Anonymous Quiz
0%
a) Slowing of the circulation
4%
b) Venular dilation
0%
c) Recruitment of vascular beds
2%
d) Capillary engorgement
94%
e) Arteriolar vasoconstriction
. Regarding chemical mediators of inflammation:
Anonymous Quiz
12%
a) Histamine is particularly produced by basophils
34%
b) Leukotrienes is a potent chemotactic agent for platelets
17%
c) C3a and C3b increase vascular permeability
37%
d) Leukotrienes are produced by neutrophils and some
7. Vascular hyperemia:
Anonymous Quiz
60%
a) is caused by inflammatory mediators
0%
b) results in cyanosis
40%
c) results in oedema
0%
d) results in brown induration
15. In acute inflammation, which is the correct sequence of events with regard to vascular flow and caliber?
Anonymous Quiz
2%
a) Vasodilation, margination, stasis, vasoconstriction
2%
b) Vasoconstriction, stasis, margination, vasodilation
93%
d) Vasoconstriction, vasodilation, stasis, margination
2%
e) Vasodilation, vasoconstriction, stasis, margination
0%
c) Vasodilation, stasis, vasoconstriction, marginaiton
17. Chronic inflammation is characterized by all of the below except:
Anonymous Quiz
5%
a) Tissue destruction
67%
b) Marked edema
7%
c) Fibrosis
21%
d) Increased tissue concentration of lymphocytes
. Which of these is not a clinical feature of inflammation?
Anonymous Quiz
4%
a) redness
85%
b) necrosis
6%
c) pain
4%
d) heat
. What is the name for the protein-rich extravascular fluid produced in inflammation?
Anonymous Quiz
3%
a) transudate
3%
b) blood
0%
c) pus
95%
d) exudate
35. During the early stages of the inflammatory response, histamine induced increased vascular permeability is most likely to occur in
Anonymous Quiz
8%
a) Arteries
30%
b) Pre-capillary arterioles
10%
c) Capillaries
43%
d) Post-capillary venules
10%
e) Veins
36. Which one of the listed substances is produced by the action of lipoxygenase on arachidonic acid, is a potent chemotactic factor for neutrophils, and causes aggregation and adhesion of leukocytes?
Anonymous Quiz
11%
a) C5a
6%
b) Prostacyclin
6%
c) IL-8
8%
d) Thromboxane A2
69%
e) Leukotriene B4
During acute inflammation, histamine-induced increased vascular permeability causes the formation of exudates (inflammatory edema)Which one of the listed cell types is the most likely source of the histamine that causes the increased vascular permeability
Anonymous Quiz
11%
a) Endothelial cells
3%
b) Fibroblasts
0%
c) Lymphocytes
84%
d) Mast cells
3%
e) Neutrophils
In acute inflammation chemotactic agents cause endothelial cell activation by all of the following except:
Anonymous Quiz
14%
a) Activation of oxidative burst
9%
b) De-granulation and secretion of enzymes
6%
c) Production of arachidonic acid metabolite
69%
d) Inhibition of cellular adhesion
3%
e) Modulation of leukocyte adhesion
39. What type of leukocyte actively participates in acute inflammatory processes and contains myeloperoxidase within its primary (azurophilic) granules and alkaline phosphatase in its secondary (specific) granules?
Anonymous Quiz
71%
a) Neutrophils
9%
b) Eosinophils
6%
c) Monocytes
3%
d) Lymphocytes
12%
e) Plasma cells
40. Histologic sections of lung tissue from a 68-year-old female with congestive heart failure and progressive breathing problems reveal numerous hemosiderin- laden cells within the alveoli. These "heart failure cells" originate from alveolar
Anonymous Quiz
3%
a) Endothelial cells
3%
b) Eosinophils
12%
c) Lymphocytes
67%
d) Macrophages
15%
e) Pneumocytes
41. By definition, granulomas are composed of:
Anonymous Quiz
0%
a) Cholesterol clefts
0%
b) Collagen
26%
c) Endothelial cells and fibroblasts
56%
d) Epithelioid cells
18%
e) Hemosiderin-laden macrophages
. Chemotatic factors may include the following except:
a) Leukotriene B4 b) Chemokine c) Nitric oxide d) Bacterial products
a) Leukotriene B4 b) Chemokine c) Nitric oxide d) Bacterial products
Anonymous Quiz
7%
a) Leukotriene B4
5%
b) Chemokine
83%
c) Nitric oxide
5%
d) Bacterial products
Which of the following is an effect of chemical mediators?
Anonymous Quiz
2%
a) Increased vascular permeability
12%
b) Chemotaxis
2%
c) Fever
83%
d) All of the above
Which of the following factors participates in the formation of inflammatory fluid exudate?
Anonymous Quiz
74%
a) Increased vascular hydrostatic pressure
5%
b) Vasoconstriction
3%
c) Decreased osmotic pressure of the interstitial tissue
18%
d) All of the above
62. What is the name of the phenomenon mediated by the selectin family?
Anonymous Quiz
2%
a) Chemotaxis
14%
b) Pavementing
5%
c) Emigration
80%
d) Rolling
63. Active movement of PMN's along a concentration gradient is known as what?
Anonymous Quiz
18%
a) Passive diffusion
59%
b) Chemotaxis
5%
c) Facilitated diffusion
18%
d) Chemotactic diffusion