TODAY: Monday 15th March: "In Westminster Hall at 16:30, there is a debate on e-petition 569957 on vaccine passports, which states: "We want the government to commit to not rolling out any e-vaccination status/immunity passport to the British public."
https://t.co/MdK5AxvZ3f
https://t.co/MdK5AxvZ3f
BBC News
The week ahead in Parliament
Law and order will dominate the Commons, but Dominic Cummings' committee appearance will turn heads.
12 Prominent Scientists and Doctors to EU Regulators: Address ‘Urgent’ Safety Concerns or Halt COVID Vaccines • Children's Health Defense
https://childrenshealthdefense.org/defender/scientists-doctors-halt-covid-vaccines/?utm_source=twitter&utm_medium=defender
https://childrenshealthdefense.org/defender/scientists-doctors-halt-covid-vaccines/?utm_source=twitter&utm_medium=defender
Children's Health Defense
12 Prominent Scientists and Doctors to EU Regulators: Address ‘Urgent’ Safety Concerns or Halt COVID Vaccines
In an open letter published this week, a group of 12 prominent scientists and doctors questioned “whether cardinal issues regarding the safety of the vaccines were adequately addressed prior to their approval” by the European Medicines Agency.
Gene editing is not just for one season, it's for life. We do not know what it will do to people next season, the one after, or in five-ten seasons. Viral vector gene therapy caused leukemia in the past after a few years. Think about it well before you agree. Astrazeneca=viral vector gene therapy: "With the development of a leukaemia-like syndrome in two of the small number of patients that have been cured of a disease by gene therapy, it is timely to contemplate how far this technology has come"
https://t.co/R4YZfe2wwH
https://t.co/R4YZfe2wwH
PubMed
Progress and problems with the use of viral vectors for gene therapy - PubMed
Gene therapy has a history of controversy. Encouraging results are starting to emerge from the clinic, but questions are still being asked about the safety of this new molecular medicine. With the development of a leukaemia-like syndrome in two of the small…
Forwarded from FUTURE NOT SET
Our appearance on @bbcworldservice at 48:20 discussing #VaccinePassports & the petition debate at #Westminster Hall
https://www.bbc.co.uk/sounds/play/w172x2wsj0ly8kc
https://www.bbc.co.uk/sounds/play/w172x2wsj0ly8kc
BBC
Newsday - 39 protesters killed in one of Myanmar's bloodiest days since coup - BBC Sounds
We go to Myanmar's largest city, Yangon, where security forces opened fire at the weekend
Forwarded from FUTURE NOT SET
REMINDER: Ursula von der Leyen & the EU will present a proposal for Digital Green Certificates this coming week.
https://twitter.com/EU_Commission/status/1369682499450904578
https://twitter.com/EU_Commission/status/1369682499450904578
Twitter
European Commission 🇪🇺
Next week we will present a proposal for digital green certificates. This digital proof that a person: has been vaccinated against COVID-19 or has recovered from COVID-19 or has a negative test result will facilitate safe free movement of citizens in the…
Forwarded from Eshani King
King, E. (2021, February 2). Vitamin D Reduces Covid-19 Mortality and Serious Illness: An Integrated Approach to Evidence. https://doi.org/10.31219/osf.io/95jsd
OSF Preprints
Vitamin D Reduces Covid-19 Mortality and Serious Illness: An Integrated Approach to Evidence
This review adopts an integrated, comprehensive approach in reviewing the emerging evidence and developments from varying sources to consolidate and add to the knowledge base on vitamin D and Covid-19. Highlighting the central role of vitamin D deficiency…
NutriXiv Preprints | The Role of Vitamin D deficiency in COVID-19 related deaths in BAME, Obese and Other High-risk Categories
https://osf.io/preprints/nutrixiv/73whx/
https://osf.io/preprints/nutrixiv/73whx/
NutriXiv
The Role of Vitamin D deficiency in COVID-19 related deaths in BAME, Obese and Other High-risk Categories
It is now widely known that a disproportionate number of COVID-19 related mortalities in the UK have
been in non-white, BAME populations [2]. The obese, diabetics, hypertensives and the elderly have
also been disproportionately affected. BAME doctors account…
been in non-white, BAME populations [2]. The obese, diabetics, hypertensives and the elderly have
also been disproportionately affected. BAME doctors account…
Forwarded from Eshani King
Robin, can I please ask you to share and implore everyone to watch and re-share this video like their life depends on it!!
A really really important video ( I asked Howard Steen to cut the German parts from a 5+hour video to leave the English parts last night and he has done an amazing job of it). If people don't realise what's going on and fight back we have no hope. Britain has no hope. CoVID itself is not a problem. It has virtually gone We need to stop focusing on that. And we really need to get people to understand the end game and why believing the CoVID narrative is taking us all down a very dangerous path.
https://lbry.tv/@LongXXvids:c/CA--43-Naomi-Wolf:0
A really really important video ( I asked Howard Steen to cut the German parts from a 5+hour video to leave the English parts last night and he has done an amazing job of it). If people don't realise what's going on and fight back we have no hope. Britain has no hope. CoVID itself is not a problem. It has virtually gone We need to stop focusing on that. And we really need to get people to understand the end game and why believing the CoVID narrative is taking us all down a very dangerous path.
https://lbry.tv/@LongXXvids:c/CA--43-Naomi-Wolf:0
Odysee
Naomi Wolf at the German Corona Investigative Committee - March 12th 2021
Massachusetts based Naomi Wolf, author (The Beauty Myth, The End of America), journalist and former political advisor talks with the German Corona Committee about the perilous state of western democra...
"In this article, we note that human host cells sensitively respond to the spike protein to elicit cell signaling. Thus, it is important to be aware that the spike protein produced by the new COVID-19 vaccines may also affect the host cells. We should monitor the long-term consequences of these vaccines carefully, especially when they are administered to otherwise healthy individuals. Further investigations on the effects of the SARS-CoV-2 spike protein on human cells and appropriate experimental animal models are warranted."
Vaccines | Free Full-Text | SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines | HTML
https://www.mdpi.com/2076-393X/9/1/36/htm
Vaccines | Free Full-Text | SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines | HTML
https://www.mdpi.com/2076-393X/9/1/36/htm
MDPI
SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines
The world is suffering from the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses its spike protein to enter the host cells. Vaccines that introduce the spike protein into…
If I can be very explicit in terms of strategy, if you don't want the vaccine passport the first thing you need to do is discredit the vaccines. There are plenty of safety grounds upon which they should be discredited. That is the nail we need to be banging with all our hammers, partially because that is how people will also save their immune systems .
REMINDER: ALL CURRENT VACCINES/GENE EDITING USE THE SARSCOV2 SPIKE PROTEIN
"Vaccines that introduce the spike protein into our body to elicit virus-neutralizing antibodies.. In this article, we note that human host cells sensitively respond to the spike protein to elicit cell signaling. Thus, it is important to be aware that the spike protein produced by the new COVID-19 vaccines may also affect the host cells."
"SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines
SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Cells
It was found that the treatment of cultured primary human pulmonary artery smooth muscle cells (SMCs) or human pulmonary artery endothelial cells with the recombinant SARS-CoV-2 spike protein S1 subunit is sufficient to promote cell signaling without the rest of the viral components [21]. Furthermore, our analysis of the postmortem lung tissues of patients who died of COVID-19 has determined that these patients exhibited pulmonary vascular wall thickening, a hallmark of pulmonary arterial hypertension (PAH) [21]. Based on these results, we proposed that the SARS-CoV-2 spike protein (without the rest of the viral components) triggers cell signaling events that may promote pulmonary vascular remodeling and PAH as well as possibly other cardiovascular complications
..Kuba et al. [28] showed that the injection of mice with recombinant SARS-CoV-1 spike protein reduced the ACE2 expression and worsened the acid-induced lung injury. In mice with an acid-induced lung injury, the recombinant SARS-CoV-1 spike protein dramatically increased angiotensin II, and the angiotensin receptor inhibitor losartan attenuated the spike protein-induced enhancement of lung injury [28]. Thus, these in vivo studies demonstrated that the spike protein of SARS-CoV-1 (without the rest of the virus) reduces the ACE2 expression, increases the level of angiotensin II, and exacerbates the lung injury.
The SARS-CoV-2 spike protein without the rest of the viral components has also been shown to activate cell signaling by Patra et al. [29]. The authors reported that the full-length SARS-CoV-2 spike protein expressed by the means of transient transfection, either in the human lung alveolar epithelial cell line A549 or in the human liver epithelial cell line Huh7.5, activated NF-κB and AP-1 transcription factors as well as p38 and ERK mitogen-activated protein kinases, releasing interleukin-6. This cell signaling cascade was found to be triggered by the SARS-CoV-2 spike protein downregulating the ACE2 protein expression, subsequently activating the angiotensin II type 1 receptor [29]. These experiments using transient transfection may reflect the intracellular effects of the spike protein that could be triggered by the RNA- and viral vector-based vaccines.
These results collectively reinforce the idea that human cells are sensitively affected by the extracellular and/or intracellular spike proteins though the activation of cell signal transduction."
https://www.mdpi.com/2076-393X/9/1/36/htm
"Vaccines that introduce the spike protein into our body to elicit virus-neutralizing antibodies.. In this article, we note that human host cells sensitively respond to the spike protein to elicit cell signaling. Thus, it is important to be aware that the spike protein produced by the new COVID-19 vaccines may also affect the host cells."
"SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines
SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Cells
It was found that the treatment of cultured primary human pulmonary artery smooth muscle cells (SMCs) or human pulmonary artery endothelial cells with the recombinant SARS-CoV-2 spike protein S1 subunit is sufficient to promote cell signaling without the rest of the viral components [21]. Furthermore, our analysis of the postmortem lung tissues of patients who died of COVID-19 has determined that these patients exhibited pulmonary vascular wall thickening, a hallmark of pulmonary arterial hypertension (PAH) [21]. Based on these results, we proposed that the SARS-CoV-2 spike protein (without the rest of the viral components) triggers cell signaling events that may promote pulmonary vascular remodeling and PAH as well as possibly other cardiovascular complications
..Kuba et al. [28] showed that the injection of mice with recombinant SARS-CoV-1 spike protein reduced the ACE2 expression and worsened the acid-induced lung injury. In mice with an acid-induced lung injury, the recombinant SARS-CoV-1 spike protein dramatically increased angiotensin II, and the angiotensin receptor inhibitor losartan attenuated the spike protein-induced enhancement of lung injury [28]. Thus, these in vivo studies demonstrated that the spike protein of SARS-CoV-1 (without the rest of the virus) reduces the ACE2 expression, increases the level of angiotensin II, and exacerbates the lung injury.
The SARS-CoV-2 spike protein without the rest of the viral components has also been shown to activate cell signaling by Patra et al. [29]. The authors reported that the full-length SARS-CoV-2 spike protein expressed by the means of transient transfection, either in the human lung alveolar epithelial cell line A549 or in the human liver epithelial cell line Huh7.5, activated NF-κB and AP-1 transcription factors as well as p38 and ERK mitogen-activated protein kinases, releasing interleukin-6. This cell signaling cascade was found to be triggered by the SARS-CoV-2 spike protein downregulating the ACE2 protein expression, subsequently activating the angiotensin II type 1 receptor [29]. These experiments using transient transfection may reflect the intracellular effects of the spike protein that could be triggered by the RNA- and viral vector-based vaccines.
These results collectively reinforce the idea that human cells are sensitively affected by the extracellular and/or intracellular spike proteins though the activation of cell signal transduction."
https://www.mdpi.com/2076-393X/9/1/36/htm
MDPI
SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines
The world is suffering from the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses its spike protein to enter the host cells. Vaccines that introduce the spike protein into…
"RBD Only-Containing SARS-CoV-2 Spike Protein Does Not Elicit Cell Signaling in Human Cells
In contrast to the full-length spike protein [26,29] or the full-length SARS-CoV-2 spike protein S1 subunit [21], we found that the RBD only-containing protein (Figure 1) did not promote cell signaling..
The different effects of the full-length S1 and RBD only-containing proteins may be important considering that BNT162b2 [PFIZER commercially produced and given in phases 2 & 3 & to the public] and many other COVID-19 vaccines express the full-length spike protein, while the BNT162b1 vaccine [PFIZER phase 1] encodes only the RBD region"
In contrast to the full-length spike protein [26,29] or the full-length SARS-CoV-2 spike protein S1 subunit [21], we found that the RBD only-containing protein (Figure 1) did not promote cell signaling..
The different effects of the full-length S1 and RBD only-containing proteins may be important considering that BNT162b2 [PFIZER commercially produced and given in phases 2 & 3 & to the public] and many other COVID-19 vaccines express the full-length spike protein, while the BNT162b1 vaccine [PFIZER phase 1] encodes only the RBD region"
Possible actions of the SARS-CoV-2 spike protein.
The SARS-CoV-2 spike protein of the intact virus targets ACE2 of the host cells to facilitate the membrane fusion and the viral entry. The SARS-CoV-2 spike protein also elicits cell signaling in human cells [21,29]. COVID-19 vaccines introduce the spike protein into the human body. In addition to eliciting an immune response that suppresses the viral entry, the spike protein produced by the COVID-19 vaccines may also affect the host cells, possibly triggering adverse events."
The SARS-CoV-2 spike protein of the intact virus targets ACE2 of the host cells to facilitate the membrane fusion and the viral entry. The SARS-CoV-2 spike protein also elicits cell signaling in human cells [21,29]. COVID-19 vaccines introduce the spike protein into the human body. In addition to eliciting an immune response that suppresses the viral entry, the spike protein produced by the COVID-19 vaccines may also affect the host cells, possibly triggering adverse events."
"Our laboratory only tested the effects of the SARS-CoV-2 spike protein in lung vascular cells and those implicated in the development of PAH [Pulmonary Arterial Hypertension]. However, this protein may also affect the cells of systemic and coronary vasculatures, eliciting other cardiovascular diseases such as coronary artery disease, systemic hypertension, and stroke. In addition to cardiovascular cells, other cells that express ACE2 have the potential to be affected by the SARS-CoV-2 spike protein, which may cause adverse pathological events. Thus, it is important to consider the possibility that the SARS-CoV-2 spike protein produced by the new COVID-19 vaccines triggers cell signaling events that promote PAH, other cardiovascular complications, and/or complications in other tissues/organs in certain individuals (Figure 3). We will need to monitor carefully the long-term consequences of COVID-19 vaccines that introduce the spike protein into the human body. Furthermore, while human data on the possible long-term consequences of spike protein-based COVID-19 vaccines will not be available soon, it is imperative that appropriate experimental animal models are employed as soon as possible to ensure that the SARS-CoV-2 spike protein does not elicit any signs of the pathogenesis of PAH or any other chronic pathological conditions."