A Decisive Blow to the #Serotonin Hypothesis of #Depression.
An exhaustive new review debunks the “chemical imbalance” theory of depression.
Surveys indicate that 85-90 percent of the public believes low serotonin or a chemical imbalance causes depression.
Among 237 psychology students interviewed, 46 percent had heard the chemical imbalance explanation from a physician.
The serotonin hypothesis has been challenged repeatedly and found wanting, even as it remains popular and influential.
A comprehensive, well-powered, high-quality umbrella review now determines that the theory is “not empirically substantiated.”
https://www.psychologytoday.com/gb/blog/side-effects/202207/decisive-blow-the-serotonin-hypothesis-depression
Major Study Finds No Evidence #Antidepressants Work
https://www.thelastamericanvagabond.com/major-study-finds-no-evidence-antidepressants-work-cdc-wont-disclose-who-working-vax-safety/
https://apnews.com/article/polio-case-new-york-4c1e2512145a1d897982f27507259d83
https://twitter.com/davidllwilliams/status/1550185545329934337
https://www.dailymail.co.uk/news/article-11033517/Have-millions-taking-antidepressants-harmful-effects-decades-no-reason.html
https://www.accessdata.fda.gov/drugsatfda_docs/nda/99/18-936S052_Prozac_Approv.pdf
https://www.sciencedaily.com/releases/2022/07/220720080145.htm
https://www.drugwatch.com/ssri/suicide/
https://www.nature.com/articles/s41380-022-01661-0
https://www.thelastamericanvagabond.com/orchestrated-addiction-masses-sweeping-epidemic-affecting-children/
https://www.cchrint.org/psychiatric-drugs/people-taking-psychiatric-drugs/
https://violationtracker.goodjobsfirst.org/parent/pfizer
#ssri #antidepressants
An exhaustive new review debunks the “chemical imbalance” theory of depression.
Surveys indicate that 85-90 percent of the public believes low serotonin or a chemical imbalance causes depression.
Among 237 psychology students interviewed, 46 percent had heard the chemical imbalance explanation from a physician.
The serotonin hypothesis has been challenged repeatedly and found wanting, even as it remains popular and influential.
A comprehensive, well-powered, high-quality umbrella review now determines that the theory is “not empirically substantiated.”
https://www.psychologytoday.com/gb/blog/side-effects/202207/decisive-blow-the-serotonin-hypothesis-depression
Major Study Finds No Evidence #Antidepressants Work
https://www.thelastamericanvagabond.com/major-study-finds-no-evidence-antidepressants-work-cdc-wont-disclose-who-working-vax-safety/
https://apnews.com/article/polio-case-new-york-4c1e2512145a1d897982f27507259d83
https://twitter.com/davidllwilliams/status/1550185545329934337
https://www.dailymail.co.uk/news/article-11033517/Have-millions-taking-antidepressants-harmful-effects-decades-no-reason.html
https://www.accessdata.fda.gov/drugsatfda_docs/nda/99/18-936S052_Prozac_Approv.pdf
https://www.sciencedaily.com/releases/2022/07/220720080145.htm
https://www.drugwatch.com/ssri/suicide/
https://www.nature.com/articles/s41380-022-01661-0
https://www.thelastamericanvagabond.com/orchestrated-addiction-masses-sweeping-epidemic-affecting-children/
https://www.cchrint.org/psychiatric-drugs/people-taking-psychiatric-drugs/
https://violationtracker.goodjobsfirst.org/parent/pfizer
#ssri #antidepressants
Psychology Today
A Decisive Blow to the Serotonin Hypothesis of Depression
An exhaustive new review debunks the “chemical imbalance” theory of depression.
#SSRI s:
They more than double a patient's risk of suicide.
- https://doi.org/10.1080/09540260500071624
They cause sexual dysfunction in 83% of patients, some of whom experience these effects even after quitting SSRIs.
- https://doi.org/10.1159/000091777
They turn patients into emotionless, apathetic zombies; the effect is dose-dependent.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2989833/
They increase risk-taking behavior, disinhibition, impulsivity.
- https://doi.org/10.1016/j.cppeds.2017.12.001
- https://www.nature.com/articles/s41598-022-13778-x
Physicians "significantly underestimate" the frequency and severity of SSRI side effects.
- https://doi.org/10.4088/jcp.v65n0712
Their NNT is 7, meaning doctors need to prescribe 7 patients SSRIs before ONE patient experiences any benefit.
- https://doi.org/10.1002/14651858.CD007954
The #serotonin theory of #depression is a lie.
- https://doi.org/10.1371/journal.pmed.0020392
- https://www.ucl.ac.uk/news/2022/jul/no-evidence-depression-caused-low-serotonin-levels-finds-comprehensive-review
29% of meta-analyses on #antidepressant trials are written by pharmaceutical company employees and 79% of authors have industry links and conflicts of interest.
- https://doi.org/10.1016/j.jclinepi.2015.08.021
#fertility
@thuletide
They more than double a patient's risk of suicide.
- https://doi.org/10.1080/09540260500071624
They cause sexual dysfunction in 83% of patients, some of whom experience these effects even after quitting SSRIs.
- https://doi.org/10.1159/000091777
They turn patients into emotionless, apathetic zombies; the effect is dose-dependent.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2989833/
They increase risk-taking behavior, disinhibition, impulsivity.
- https://doi.org/10.1016/j.cppeds.2017.12.001
- https://www.nature.com/articles/s41598-022-13778-x
Physicians "significantly underestimate" the frequency and severity of SSRI side effects.
- https://doi.org/10.4088/jcp.v65n0712
Their NNT is 7, meaning doctors need to prescribe 7 patients SSRIs before ONE patient experiences any benefit.
- https://doi.org/10.1002/14651858.CD007954
The #serotonin theory of #depression is a lie.
- https://doi.org/10.1371/journal.pmed.0020392
- https://www.ucl.ac.uk/news/2022/jul/no-evidence-depression-caused-low-serotonin-levels-finds-comprehensive-review
29% of meta-analyses on #antidepressant trials are written by pharmaceutical company employees and 79% of authors have industry links and conflicts of interest.
- https://doi.org/10.1016/j.jclinepi.2015.08.021
#fertility
@thuletide
Taylor & Francis
Antidepressant drug use & the risk of suicide
There have been longstanding concerns about the propensity of antidepressants to precipitate suicidality in vulnerable individuals. To investigate this further, first we have analyzed all clinical ...