All of the following statements concerning IgM are true EXCEPT:
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60%
It is present in blood and extracellular fluids
0%
it is the major antibody in the primary immune response
10%
It cannot cross the placental barrier
30%
It is the most efficient complement fixing antibody
Which of the following statements about IgM is true:
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5%
It is the secretory antibody
90%
It is important in the first few days of the primary immune response
5%
It is the smallest of the immunoglobulin molecules
0%
It is involved in allergic reactions
Which is the most efficient complement-fixing antibody?
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73%
IgM
19%
igG
0%
IgE
8%
Secretory IgA
0%
Serum IgA
Diagnosis of Infection in the newborn depends on the detection of:
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13%
IgG
71%
IgM
3%
IgE
3%
Secretory IgA
10%
Serum IgA
IgA is characterized by the following EXCEPT:
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11%
it may exist in monomaniac or dimmer form
7%
It provides immunity at mucosal surface
7%
It is protected from proteolytic cleavage by secretory piece
75%
it can cross the placental barrier.
The secretory component of IgA is synthesized by:
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79%
Local mucosal cells
14%
B-cells
0%
Endothelial cells
7%
Plasma cells
The main antibody in secretions protecting outer surfaces of mucosal membranes are:
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10%
IgA and IgE
3%
IgE and IgD
7%
IgM and IgG
69%
IgA
10%
IgA and IgM
The following immunoglobulin provides local immunity at the mucosal surfaces:
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3%
IgM
0%
IgD
94%
IgA
3%
IgG
0%
IgE
All of the following are examples of how acquired immunity can help innate immunity EXCEPT:
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8%
Macrophage activation by Th1 celis
50%
Antigen presentation to T cells
17%
NK cell activation by IL-2 to give LAK cells
8%
Antibody-mediated opsonization
17%
ADCC
Immunoglobulin class switching is mediated by a change in;
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76%
Constant domains of heavy chains
4%
Constant domains of light chains
12%
Variable domain of heavy chain
8%
Constant domain of both heavy and light chain
Regarding the primary immune response:
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12%
There is a very short induction (lag) period
84%
Immunoglobulins produced are mainly of IgM class
4%
Memory cells are the main effector cells
0%
The induced antibody level is very high
In primary immune response:
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11%
There is a short induction period
82%
There is no memory cells
4%
The predominant immunoglobulin IgG
4%
The antibody level is very high
The monoclonal antibody is characterized by the following EXCEPT:
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7%
Highly specific
79%
- Produced by different clones or B cells
7%
Can be artificially produced
7%
Can be used in diagnosis or therapy
Which antibody provides local Immunity at the mucosal surfaces:
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97%
IgA
0%
IgD
0%
IgE
3%
IgG
Which surface molecule delivers the first signal for B-cell activation
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71%
B cell receptor
6%
B7
15%
CD40
9%
MHCI
هينزل باقي أسئلة GIT من كتاب القسم لو عايز ترجع لباقي الأسئلة اضغط هنا!
45-" Larva currens" is the name given to the migrating larva of:
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9%
a) Ancylostoma duodenale
2%
b) Trichostrongylus colubriformis
86%
c) Strongyloides stercoralls
3%
d) Capillaria philippinensis