A surface molecule on B cells essential for antigen presentation is:
Anonymous Quiz
30%
B cell receptor (BCR)
9%
CD40
61%
MHCII
0%
Immunoglobulin
Activation of naΓ―ve mature B cells requires the following EXCEPT:
Anonymous Quiz
10%
Surface antibody contact with antigen
10%
T cell cytokine stimulation
14%
8 cell CD40 interaction with T cell CD40
67%
Antigen presentation to T cell via class I MHC
The second signal in activation of naΓ―ve B cells includes all of the following EXCEPT:
Anonymous Quiz
37%
Antigen binding to B cell receptor
5%
Activated helper T cells
37%
Engulfment and degradation of the bound antigen by B cell
21%
Peptide presentation on the B cell surface in association with MHC II
The role of macrophages during antibody formation is:
Anonymous Quiz
11%
Production of cytokines
84%
Processing and presentation of antigens to CD4 T helper cells
0%
Activation of CD8 T cytotoxic cells
5%
Promotion of development of Thi cells
Which of the following has an effect on humoral immunity?
Anonymous Quiz
11%
Activation of cytotoxic CD8 T cells
11%
Lysis of virus infected cells
74%
Processing and presentation of antigen to T helper cells
5%
Activation of NK cells
All of the following statements about memory cells are true EXCEPT:
Anonymous Quiz
6%
They are produced in response to thymus-dependent antigens
6%
They are responsible for immunological memory
89%
They are short-lived cells
0%
They are produced following the primary immune response
Thymus Independent (TI) antigens
Anonymous Quiz
6%
Can stimulate B cells through T cell help
89%
Do not produce memory cells.
6%
Can stimulate immunoglobulin class switching
0%
Can only induce the production of IgG
The heavy chain of immunoglobulin consists of:
Anonymous Quiz
10%
One variable and two constant domains
20%
Two variable and one constant domain
10%
One variable one constant domain
60%
One variable and three or four constant domains
Opsonization depend on presence of the following structures on surface of phagocytic cells:
Anonymous Quiz
5%
Foreceptors
32%
C3b receptors
0%
CBCR
47%
a&b
16%
a&c
Regarding ADCC, all the following are true EXCEPT:
Anonymous Quiz
53%
it occurs through apoptosis of the target cell
0%
It may be mediated by NK cells
21%
It is a cytotoxic reaction against an antibody-coated cell
26%
It is an example of enhancing of innate immunity by specific Immunity
Which of the following cells is involved in ADCC:
Anonymous Quiz
5%
CD4 cell
0%
CD8 cell
16%
Mature B cell
79%
Natural killer (NK) cell
All the following statements are true about IgG EXCEPT:
Anonymous Quiz
58%
It is an example of enhancing of innate immunity by specific Immunity
16%
it can pass the placenta barrier to the fetal circulation
11%
It is the major antibody of the secondary immune response
16%
Anti-Rh antibodies are of the IgG glass
All of the following statenments concerning IgG are true EXCEPT:
Anonymous Quiz
82%
it is the major antibody of the primary immune response
0%
It is composed of a single basic unit (monomer
12%
It is the only antibody that can cross the placenta
6%
it is the principal isotype in blood and extracellular fluids
The major immunoglobulin present in the human serum is:
Anonymous Quiz
9%
igA
0%
IgD
4%
IgE
78%
igG
9%
IgM
The only immunoglobulin class which can cross the placenta is:
Anonymous Quiz
5%
IgM
0%
IgA
86%
IgG
5%
IgD
5%
IgE
The only immunoglobulin to thymus independent (TI) antigen is:
Anonymous Quiz
70%
IgM
5%
IgA
0%
IgG
10%
IgD
15%
IgE