Mutflash - Medizinische Argumentationen und Studiensammlungen
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Sweden opts for coronavirus protein vaccine instead of mRNA

From the 2027/2028 season onwards, Sweden will use only a protein-based coronavirus vaccine for its national vaccination campaign. It is the first country in the world to say goodbye to the problematic mRNA vaccines from Pfizer and Moderna.

https://artsencollectief.nl/zweden-kiest-voor-corona-eiwitvaccin-in-plaats-van-mrna/
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https://x.com/CanningPharm/status/2115442628770627926

Narf! Der Marciboy blickt es mal wieder nicht:

Marc Girardot vermischt zwei unterschiedliche Faktoren: die Geschwindigkeit der Verabreichung und die biologischen Eigenschaften der verabreichten Formulierung. Beides kann für die Sicherheit relevant sein, ist aber nicht dasselbe:

Bei der IV-Verabreichung von lebendem BCG waren 9 von 10 Rhesusaffen stark vor Tuberkulose geschützt; bei 6 war keine Infektion nachweisbar. Die beobachteten immunologischen Veränderungen gingen weitgehend zurück. BCG ist ein lebender bakterieller Impfstoff, mRNA-Impfstoffe verwenden dagegen Lipidnanopartikel (LNP) als Trägersystem. Die biologischen Eigenschaften und Wirkmechanismen unterscheiden sich grundlegend. Die Studie zeigt, dass die intravenöse Route mit einem geeigneten Impfstoff nicht zwangsläufig schädlich ist.

https://www.nature.com/articles/s41586-019-1817-8

Verglich langsamere und schnellere intravenöse Flüssigkeitsboli. Die 90-Tage-Sterblichkeit unterschied sich nicht signifikant: 26,6 % gegenüber 27,0 %. Das widerspricht der pauschalen Annahme, eine langsamere IV-Gabe sei grundsätzlich sicherer. Untersucht wurden allerdings Infusionslösungen, keine Impfstoffe.

https://pmc.ncbi.nlm.nih.gov/articles/PMC8356145/

Bei einer IV-Immunglobulin-Zubereitung waren Infusionsraten bis 0,14 ml/kg/min insgesamt gut verträglich; infusionsbedingte Nebenwirkungen nahmen nicht eindeutig mit der Geschwindigkeit zu. Das zeigt, dass der Zusammenhang vom konkreten Präparat abhängt.

https://pubmed.ncbi.nlm.nih.gov/17109385/

Girardots allgemeine Erklärung greift(wie immer) zu kurz: Zusammengenommen sprechen die drei Studien gegen die pauschale Regel „je schneller, desto gefährlicher“: Das Risiko hängt auch von Substanz, Formulierung, Dosis und klinischem Kontext ab. Sie beweisen nicht, dass die Geschwindigkeit bei mRNA/LNP-Impfstoffen irrelevant ist – wohl aber, dass sie keine universelle Erklärung für die Gefährlichkeit einer intravenösen Gabe darstellt.

https://substack.com/profile/50562652-genervter-burger/note/c-372681516
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Maria und ich diskutieren immer noch über Marc Girardot's Ignoranz. Mein Argument gegen seine Hypothese:

Two injection techniques were compared: a rapid injection with quick needle withdrawal without aspiration, and a slower technique with aspiration and slow needle withdrawal. The rapid technique caused less acute pain and shorter crying episodes. No adverse events were observed.

https://pubmed.ncbi.nlm.nih.gov/17686797/

The study compared rapid and slow vaccine injections. For the DTaP-IPV-Hib vaccination, the pain response was lower with the rapid injection; for the pneumococcal vaccination, this difference was not observed. Other outcomes examined did not differ significantly.

https://pubmed.ncbi.nlm.nih.gov/27527817/

Following intramuscular administration of the antibiotic carbenicillin, peak serum concentrations were not reached until several hours later. The authors described delayed absorption in the youngest newborns.

This shows that intramuscular absorption and systemic concentration kinetics may depend on age and the substance itself. It contradicts the blanket assumption that every IM injection is equivalent to immediate IV administration.

https://pubmed.ncbi.nlm.nih.gov/422253/

An important but different finding is the case series by Wynne et al. (1978). It describes three infants who received accidental intra-arterial injections of antibiotics, resulting in severe vascular occlusions and gangrene.

https://adc.bmj.com/content/53/5/396

The measurements show that systemic exposure following IM administration does not simply correspond to that of direct IV administration—even in a neonatal model. However, the study did not determine the exact intravascular fraction of the dose and did not vary the injection rate.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12468923/

Svendsen’s study is relevant because it directly compares fast and slow IM injections. However, the study examined local tissue damage in rabbits, not the proportion of the dose in the blood.

https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-0773.1983.tb01105.x

Another study, by Styf (1989), measured intramuscular pressure following injection. It shows that the measured pressure values depend heavily on the measurement method. However, this study also did not measure the intravascular fraction of the dose.

https://pubmed.ncbi.nlm.nih.gov/2795320/

+

https://substack.com/profile/50562652-genervter-burger/note/c-372681516

Taken together, these findings provide no empirical support for Marc’s specific mechanism. The injection-technique studies show that faster administration can reduce pain in one vaccine comparison, while this effect is not consistent across vaccines. Svendsen’s study found that injection speed was not an important factor in local tissue damage overall. The neonatal pharmacokinetic findings show that IM absorption can be delayed and age-dependent, and that early plasma concentration profiles following IM administration do not simply reproduce those following IV administration.

None of these studies demonstrates that a substantial fraction of an IM vaccine dose is forcibly driven into the bloodstream by injection pressure. Nor does any of them demonstrate that this fraction increases with injection speed in newborns.

The differences observed in these studies cannot be explained simply by invoking a pressure-driven intravascular bolus. Such an explanation requires evidence that the proposed bolus actually occurs, that its magnitude depends on injection speed, and that it accounts for the observed effects. The cited studies provide no such evidence. Instead, their findings undermine the assumption that rapid IM injection can simply be treated as equivalent to immediate IV delivery. Girardot’s bolus mechanism therefore remains an unsubstantiated hypothesis, not an established physiological fact.

I agree that additional physical and anatomical processes can occur before cellular uptake, including interactions with proteins in the bloodstream and age-dependent differences in biological barriers. But those processes do not, by themselves, establish Girardot’s bolus mechanism.
Bin megagespannt!
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Forwarded from BastaBerlin (Benjamin)
Paul Brandenburg wurde vorgestern in Berlin festgenommen. Er sitzt in Untersuchungshaft in Moabit. Laut Markus Haintz wird ihm Beleidigung des regierenden Bürgermeisters vorgeworfen. Als Haftgrund wird Fluchtgefahr genannt. Allerdings kommt er laut Haintz immer wieder nach Berlin. Und natürlich wusste er das etliche Verfahren gegen ihn laufen.
Paul Brandenburg hat in den vergangenen fünfeinhalb Jahren sehr viel für die deutsche Opposition getan. Auch für Basta Berlin und ich habe ihn als faszinierenden Menschen kennengelernt. Ich wünsche ihm heute viel Kraft.
Benjamin

https://x.com/haintz_medialaw/status/2116032352858317106?a=OGKtFDnft-OibwZdmdU&s=46
"A qualitative approach using Bradford Hill's criteria provides partial, inconclusive evidence of a causal relationship while also exposing the methodological limits of the tool employed. The results of the analysis showed that one of the nine criteria demonstrated support of causality, seven were partially supported, and one did not support causality. The analysis suggests, but does not prove, a causal relationship between the BNT162b2 vaccine and multifocal necrotizing encephalitis. The absence of the nucleocapsid protein does not provide definitive evidence to demonstrate a vaccine origin. Analytical methods are described which can distinguish between the wild-type SARS-CoV-2 spike protein and the recombinant spike protein expressed following mRNA vaccination. The absence of evidence does not mean evidence of absence and we must keep an open mind to this when reviewing such evidence on causality."

Siebner AS, Rubio-Casillas A, Raszek M, et al. Beyond correlation and causation: epistemic caution, anomalous findings, and COVID-19 vaccine safety. Philos Ethics Humanit Med. 2026;21(1):28. Published 2026 Oct 1. doi:10.1186/s13010-026-00232-3
https://apolut.net/tag/im-gespraech/

Ok... Langsam hege ich leise Zweifel, dass das Gespräch mit Markus Fiedler noch erscheinen wird. 🤔

UPDATE

Ok. Hab jetzt endlich ne feste Terminansage: 09.11.2026
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https://www.youtube.com/watch?v=Ou47nWET6Mw

Point 4 bezieht sich auf unser Paper! Ich kann es kaum erwarten, wenn er das Video rausballert!
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Maria hat die Bombe aller Bomben gefunden:

The Impact of Magnesium Ions on The Fidelity of T7 RNA Polymerases

A surprisingly high mutation rate was observed in RNA synthesized under high magnesium concentrations (8 mM and 12 mM), raising significant safety concerns for most current RNA-based therapeutics.


RNA has become a key element of modern therapeutics, with in vitro transcription (IVT) as the primary method of production. Elevated magnesium concentrations are frequently employed to enhance yield. Quality assurance protocols generally focus on evaluating double-stranded RNA content and size consistency. The fidelity of wild-type and engineered T7 RNA polymerase (RNAP) at different magnesium levels was compared in this study. Our data showed that the two enzymes exhibited distinct patterns of mutation hotspots. IVT performed with 8 mM magnesium ions led to mutational events that rendered 70% and 80% of full-length self-amplifying RNA nonfunctional, respectively. At 4 mM magnesium, both RNAPs showed high fidelity, except for one truncated cDNA clone produced by the modified T7 RNAP. Our observation underscores the need to assess both RNA yield and integrity when determining optimal IVT reaction parameters

https://www.ncbi.nlm.nih.gov/bioproject/1520612

Kurz:

Die wussten ALLES! Die hatten die Wahl zwischen mehr DNA und weniger RNA-Mutationen oder mehr DNA und weniger RNA-Mutationen.
https://t.me/mspezial/21261

https://t.me/mspezial/21258

Narf?! Wohlwissend, dass Stebel mal wieder GAR NICHTS kapiert, kann sie sich mit Marc die Hand reichen.

https://x.com/sabisteb/status/2116134252949463152?s=12

"The proposed mechanism of injury is the unintentional injection of antigenic material into synovial tissues resulting in an immune-mediated inflammatory reaction."

https://pubmed.ncbi.nlm.nih.gov/20955829/

Stebels eigene Referenzen zeigen, wie ignorant sie ist! Es ist kein mechanischer Schaden.
Forwarded from VERBORGENE WAHRHEIT 👁‍🗨
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Ein urkomischer, zwei Minuten langer Sketch fängt den Wahnsinn der COVID-Zeit perfekt ein.

— Niko

Abonniere den Kanal — es erwartet dich viele wichtige Informationen: @Verborgene_Wahrheit 👁‍🗨
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